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Outpatient Treatment of Gram Positive Wound Infections in the Diabetic Foot: A Pharmaco-economic Comparison of Daptomycin vs. Vancomycin Based Regimens

2014-07-23 21:08:56 | BioPortfolio

Summary

The purpose of the study is to evaluate the overall burden to the participant (economic, quality of life, patients satisfaction and freedom from side effects) when treating Gram positive infections of the foot in diabetic adults with daptomycin versus vancomycin.

Description

1. to compare the overall economic burden of therapy of a daptomycin vs. a vancomycin based antibiotic regimen for diabetic foot infections in the outpatient setting

2. to compare Quality of Life and patient satisfaction among recipients of a daptomycin vs. a vancomycin based regimen

3. to compare the safety and tolerance (adverse experiences) of daptomycin vs. vancomycin based regimens

4. to compare the efficacy (complete resolution of infection) of daptomycin vs. vancomycin based regimens

Study Design

Allocation: Randomized, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Diabetic Foot

Intervention

Cubicin, Vancomycin

Location

Infuscience
Annandale
Virginia
United States
22003

Status

Terminated

Source

Clinical Alliance for Research & Education - Infectious Diseases, LLC.

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-23T21:08:56-0400

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Medical and Biotech [MESH] Definitions

Common foot problems in persons with DIABETES MELLITUS, caused by any combination of factors such as DIABETIC NEUROPATHIES; PERIPHERAL VASCULAR DISEASES; and INFECTION. With the loss of sensation and poor circulation, injuries and infections often lead to severe foot ulceration, GANGRENE and AMPUTATION.

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Devices used to support or align the foot structure, or to prevent or correct foot deformities.

Distortion or disfigurement of the foot, or a part of the foot, acquired through disease or injury after birth.

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