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Effect of Maraviroc on Metabolic Function in Obese Subjects (Phase I)

2014-08-27 03:13:20 | BioPortfolio

Summary

The purpose of this study is to determine the effect of maraviroc therapy in obese insulin resistant subjects on:

1. Plasma triglyceride concentration

2. Plasma HDL-cholesterol and LDL-cholesterol concentrations

3. Plasma markers of cardiometabolic risk and inflammation

Description

The purpose of this study is to determine, in obese insulin resistant subjects, the effect of maraviroc therapy, a selective antagonist of the human chemokine receptor CCR5, on:

1. Plasma triglyceride concentration

2. Plasma HDL-cholesterol and LDL-cholesterol concentrations

3. Plasma markers of cardiometabolic risk and inflammation

Study Design

Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment

Conditions

Hypertriglyceridemia

Intervention

Maraviroc, placebo

Location

Washington University School of Medicine
St. Louis
Missouri
United States
63110

Status

Not yet recruiting

Source

Washington University School of Medicine

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:13:20-0400

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