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Transcranial Direct Current Stimulation (TDCS) for Facilitating Swallowing Improvement After an Acute Unilateral Hemispheric Stroke

2014-08-27 03:13:22 | BioPortfolio

Summary

Swallowing disorders are common after a stroke but effective treatments are currently lacking. Hemispheric strokes, which denote strokes that are confined to the cerebral hemispheres occur frequently in general population and often produce swallowing impairments. In this pilot study, the investigators plan to investigate the efficacy of a novel cortical stimulation technique, tDCS for improving swallowing impairments in patients who develop swallowing impairments after an acute hemispheric (Stroke that involves the cerebral hemispheres of the brain) ischemic stroke. All patients will be randomized to receive anodal tDCS versus sham.

Description

We will enroll acute ischemic stroke patients from our inpatient stroke service with dysphagia between 24-168 hours after stroke. Patients with moderate to severe dysphagia will be enrolled using validated swallowing assessment by a speech and swallow pathologist. The swallowing assessments will be recorded by a speech and language pathologist blinded to the stimulation allocation. The subjects will be randomized to receive anodal tDCS versus sham stimulation over the swallowing cortex in conjunction with standardized swallowing maneuvers. Sham stimulation is subjectively indistinguishable from tDCS. A final swallowing assessment will be made after the final session of tDCS/sham. The relative differences in swallowing improvements between the 2 groups will be computed.

Study Design

Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Outcomes Assessor), Primary Purpose: Treatment

Conditions

Dysphagia

Intervention

tDCS, Sham

Location

Beth Israel Deaconess Medical Center
Boston
Massachusetts
United States
02215

Status

Recruiting

Source

Beth Israel Deaconess Medical Center

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:13:22-0400

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