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Prevention of Drug Induced Ototoxicity in Peritoneal Dialysis Patients by N-Acetylcysteine

2014-08-27 03:13:22 | BioPortfolio

Summary

The purpose of this study is to determine whether N-acetylcysteine is effective in the prevention of hearing loss in both ears due to aminoglycoside and/or vancomycine induced ototoxicity in peritoneal dialysis patients.

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention

Conditions

Drug-induced Ototoxicity in Peritoneal Dialysis Patients

Intervention

N-acetylcysteine

Location

Erciyes University School of Medicine Department of Nephrology
Kayseri
Turkey
38039

Status

Completed

Source

TC Erciyes University

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:13:22-0400

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Medical and Biotech [MESH] Definitions

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Dialysis fluid being introduced into and removed from the peritoneal cavity as either a continuous or an intermittent procedure.

Disorder characterized by a wide range of structural changes in PERITONEUM, resulting from fibrogenic or inflammatory processes. Peritoneal fibrosis is a common complication in patients receiving PERITONEAL DIALYSIS and contributes to its gradual decrease in efficiency.

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Cyclic basic peptide related to VIOMYCIN. It is isolated from an induced mutant of Streptomyces griseoverticillatus var. tuberacticus and acts as an antitubercular agent with less ototoxicity than tuberactinomycin.

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