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First-in-Human Single Ascending Dose of GLPG0492

2014-08-27 03:13:26 | BioPortfolio

Summary

The purpose of the study is to evaluate the safety and tolerability of single ascending (SAD) oral dose of GLPG0492 compared to placebo in healthy subjects.

Also, pharmacokinetics (PK) and pharmacodynamics (PD) of GLPG0492 after single oral administration will be evaluated, and, if applicable, the maximum tolerated dose determined. Oral bioavailability (solution vs solid capsule fasting or fed) is evaluated in healthy elderly subjects.

Study Design

Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Safety Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor)

Conditions

Healthy

Intervention

GLPG0492, placebo, GLPG0492, GLPG0492

Location

SGS Stuivenberg
Antwerp
Belgium

Status

Active, not recruiting

Source

Galapagos NV

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:13:26-0400

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