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The aims of this study are to explore the various cognitive impairments of ADHD children, to differentiate various subtypes of ADHD children, and to investigate the efficacy of anti-ADHD drugs on various cognitive performance of ADHD children by event-related potentials(ERP).
Children, aged six to 18 years old, are enrolled and assigned to three groups (normal control, pure ADHD, and ADHD with comorbidities). ADHD children fulfill the DSM-IV-TR criteria for the diagnosis of ADHD. ADHD children are evaluated by Chinese version of SNAP-IV Rating Scale for rating ADHD-related symptoms before and after medication. EEG and audiometric testing are required for every participant to exclude dialeptic seizures and hearing impairment respectively.
Methylphenidate (either immediate-release or extended-release formulations), atomoxetine Hydrochloride or magnesium-vitamin B6 supplement is given to ADHD participants.Continuous performance task (CPT) and ERP tasks are applied.
Intervention Model: Parallel Assignment
Attention Deficit Disorders With Hyperactivity
methylphenidate, Atomoxetine, behavioral modification
Children Hospital, National Taiwan University Hospital
Far Eastern Memorial Hospital
Published on BioPortfolio: 2014-08-27T03:13:26-0400
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PIEVSKY, M. A., and R. E. McGrath. Neurocognitive effects of methylphenidate in adults with attention-deficit/hyperactivity disorder: A meta-analysis…NEUROSCI BIOBEHAV REV 81(1) XXX-XXX, 2017.- This...
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