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The Effect of DHEA on Markers of Ovarian Reserve in Women With Diminished Ovarian Reserve

2014-07-23 21:08:59 | BioPortfolio

Summary

This prospective study evaluates the effect of DHEA supplementation on markers of ovarian reserve in women with diminished ovarian reserve.

Description

Ovarian reserve markers, such as FSH, estradiol, AMH, ovarian volume and antral follicle counts will be monitored on DHEA supplementation in a prospective fashion.

Study Design

Allocation: Non-Randomized, Control: Uncontrolled, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Women With Diminished Ovarian Reserve

Intervention

dehydroepiandrosterone

Location

Virginia Center for Reproductive Medicine
Reston
Virginia
United States
20190

Status

Recruiting

Source

Virginia Center for Reproductive Medicine

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-23T21:08:59-0400

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Medical and Biotech [MESH] Definitions

Capacity of the ovary to provide viable eggs.

A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.

Men and women serving on active duty in the military, or in a reserve military force, and their immediate family including spouses, children, and parents.

The period before MENOPAUSE. In premenopausal women, the climacteric transition from full sexual maturity to cessation of ovarian cycle takes place between the age of late thirty and early fifty.

Cessation of ovarian function after MENARCHE but before the age of 40, without or with OVARIAN FOLLICLE depletion. It is characterized by the presence of OLIGOMENORRHEA or AMENORRHEA, elevated GONADOTROPINS, and low ESTRADIOL levels. It is a state of female HYPERGONADOTROPIC HYPOGONADISM. Etiologies include genetic defects, autoimmune processes, chemotherapy, radiation, and infections.

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