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Effect of Aromatase Inhibitors on Breast Magnetic Resonance Imaging (MRI)

2014-08-27 03:13:27 | BioPortfolio

Summary

This study is a primary investigation to determine the usefulness and safety of a short course of a relatively high dose of letrozole (a medication used to decrease the female hormone estrogen which is produced locally inside the breast after menopause) in improving the performance of of breast MRI (Magnetic Resonance Imaging). The inhibition of estrogen in the breast by letrozole might help better identifying of suspicious areas in the breast and could assist radiologists in distinguishing between benign breast areas and cancer tissue. This might help reducing the rate of call backs and unnecessary biopsies for patients. We expect to enroll 20 healthy postmenopausal women in this study.

Study Design

Allocation: Non-Randomized, Control: Uncontrolled, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic

Conditions

Postmenopause

Intervention

letrozole

Location

Mount Sinai Hospital
Toronto
Ontario
Canada
M5T 3H7

Status

Active, not recruiting

Source

Mount Sinai Hospital, Canada

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:13:27-0400

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Medical and Biotech [MESH] Definitions

The physiological period following the MENOPAUSE, the permanent cessation of the menstrual life.

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