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Enamel Remineralization Potential of Dentifrices in Situ

2014-07-23 21:08:59 | BioPortfolio

Summary

This study will use an oral in situ caries model to study remineralization of enamel due to the action of different combinations of fluoride salts delivered from dentifrices.

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Outcomes Assessor), Primary Purpose: Prevention

Conditions

Dental Caries

Intervention

Fluoride Toothpaste 1, Reference Dentifrice, Fluoride Toothpaste 2, Fluoride Toothpaste 3

Location

GSK Investigational Site
Indianapolis
Indiana
United States
46202

Status

Completed

Source

GlaxoSmithKline

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-23T21:08:59-0400

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Medical and Biotech [MESH] Definitions

Calcium fluoride. Occurring in nature as the mineral fluorite or fluorspar. It is the primary source of fluorine and its compounds. Pure calcium fluoride is used as a catalyst in dehydration and dehydrogenation and is used to fluoridate drinking water. (From Merck Index, 11th ed)

A dentifrice in paste form; usually contains binder, humectant, an abrasive, a detergent, flavoring agent and often caries preventives, anti-infective agents or other medicaments.

A source of inorganic fluoride which is used topically to prevent dental caries.

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Poisoning that results from chronic or acute ingestion, injection, inhalation, or skin absorption of FLUORIDE compounds.

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