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Canthaxanthin Retinopathy: A Long-term Observation

2014-08-27 03:13:32 | BioPortfolio

Summary

Canthaxanthine is a naturally occurring carotenoid that has been a popular over-the-counter oral artificial tanning agent in Europe, Canada, and Australia since 1979. It is also used at low dosage as a food-colouring agent and as a therapeutic agent for photosensitivity disorders such as erythropoietic protoporphyria. Canthaxanthin retinopathy was first described in 1982 by Cortin et al. In Germany the office of the federal board of health refused the permit for oral tanning agents containing canthaxanthine in 1985. At that time the long-term course of the disease was not known. 25 years later the investigators did these long-term follow-up examinations.

Study Design

Observational Model: Case-Only, Time Perspective: Prospective

Conditions

Canthaxanthin Retinopathy

Location

University Eye Hospital, University of Cologne
Cologne
NRW
Germany
50937

Status

Completed

Source

University of Cologne

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:13:32-0400

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Medical and Biotech [MESH] Definitions

A trans-carotenoid pigment widely distributed in nature. The compound is used as an oral suntanning agent and as a food and drug coloring agent. Oral ingestion of the compound causes canthaxanthin retinopathy.

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