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Effects of Cultura Yoghurt in Irritable Bowel Syndrome (IBS) Patients on Intestinal and Immunological Changes

2014-08-27 03:13:32 | BioPortfolio

Summary

To determine the effect of cultura probiotic yoghurt on number of responders to treatment during 8 weeks of treatment in comparison to placebo. To determine the effect of cultura yoghurt on change in total score of (IBS) irritable bowel syndrome severity index during 8 weeks of treatment in comparison to placebo in IBS out patients.

Description

Recent research has shown taht probiotic may give positive effect on symptoms among patients with (IBS) Irritable Bowel Syndrome. The mechanism behind the positive effect are not known but a positive effect on different cytokines are a possible mechanism. Also effect on the large intestine bacterial mass could be of importance.

Study Design

Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment

Conditions

Irritable Bowel Syndrome

Intervention

Arla Yoghurt with no probiotic, Probiotic yoghurt (Cultura)

Location

Department of Internal Medicine, Sahlgrenska University Hospital
Gothenburg
Sweden
41345

Status

Completed

Source

Good Food Practice, Sweden

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:13:32-0400

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Medical and Biotech [MESH] Definitions

A subspecies of Bifidobacterium longum that occurs in the GASTROINTESTINAL TRACT of human infants and is used as a PROBIOTIC. It may also be used in the treatment of IRRITABLE BOWEL SYNDROME.

A species of Bifidobacterium present in the human GUT MICROBIOTA. It is used as a PROBIOTIC.

A species of Saccharomyces that is used as a PROBIOTIC, such as in the treatment of DIARRHEA and PSEUDOMEMBRANOUS ENTEROCOLITIS associated with CLOSTRIDIUM INFECTIONS.

An alkalophilic species of Bacillus that occurs in soil. It produces ANTI-BACTERIAL AGENTS and is used as a PROBIOTIC.

A species of Lactobacillus that occurs in the human GASTROINTESTINAL TRACT and ORAL MUCOSA. It produces BACTERIOCINS and is used as a PROBIOTIC.

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