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Lidocaine Analgesia For Removal Of Wound Vac Dressings

2014-08-27 03:13:34 | BioPortfolio

Summary

The purpose of this prospective study is to compare pain levels in patients with topical negative pressure (TNP) dressings removed in a standard manner (i.v. or p.o. pain meds) compared to dressings removed after normal saline or lidocaine is injected retrograde up the suction tube into the foam prior to removal. Our null hypothesis is that there will be no difference in overall pain scores between the groups receiving saline injection and pain medications or just pain medications, compared to those with lidocaine injection and pain medications. Our objective is to disprove this null hypothesis with statistical significance.

Study Design

Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Supportive Care

Conditions

Analgesia

Intervention

Lidocaine, Placebo

Location

University of Utah
Salt Lake City
Utah
United States
84112

Status

Completed

Source

University of Utah

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:13:34-0400

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Medical and Biotech [MESH] Definitions

Analgesia produced by the insertion of ACUPUNCTURE needles at certain ACUPUNCTURE POINTS on the body. This activates small myelinated nerve fibers in the muscle which transmit impulses to the spinal cord and then activate three centers - the spinal cord, midbrain and pituitary/hypothalamus - to produce analgesia.

Misunderstanding among individuals, frequently research subjects, of scientific methods such as randomization and placebo controls.

Antiarrhythmic agent pharmacologically similar to LIDOCAINE. It may have some anticonvulsant properties.

An effect usually, but not necessarily, beneficial that is attributable to an expectation that the regimen will have an effect, i.e., the effect is due to the power of suggestion.

A local anesthetic that is similar pharmacologically to LIDOCAINE. Currently, it is used most often for infiltration anesthesia in dentistry. (From AMA Drug Evaluations Annual, 1992, p165)

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