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Adenosine Cardioplegia; Improved Cardioprotection?

2014-08-27 03:13:41 | BioPortfolio

Summary

60 elective patients for CABG will be included to receive either standard hyperkalemic cardioplegia (St.Thomas Hospital Solution No I) or cardioplegia where supranormal potassium is replaced with 1.2 mM adenosine. Hypothesis as follows: 1. Adenosine instead of supranormal potassium in the cardioplegic solution give satisfactory cardiac arrest. 2. Adenosine instead of supranormal potassium in the cardioplegic solution gives equal cardioprotection. The patients will be followed with PiCCO-catheter to monitor cardiac function and repetitive blood samples to measure release of cardiac enzymes.

Study Design

Allocation: Randomized, Control: Active Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Conditions

Angina Pectoris

Intervention

Adenosine

Location

University Hospital of North Norway
Troomsø
Norway
9038

Status

Recruiting

Source

University Hospital of North Norway

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:13:41-0400

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