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Transplantation of Cultivated Corneal Epithelial Sheet in Patients With Ocular Surface Disease

2014-08-27 03:13:41 | BioPortfolio

Summary

The aim of the study is to assess if transplantation of cultivated corneal epithelial stem cells could restore vision in patients with severe ocular surface disorder with a favourable safety profile that warrants further comparative study.

Description

Objectives:

Efficacy:

To determine the efficacy of cultivated corneal epithelial stem cells as a treatment for patients with severe ocular surface disorder.

The corneal limbal epithelial stem cell transplant (CLET) successful outcome will be measured by improvement of vision, maintenance of corneal re-epithelisation with absence of recurrence of surface disease and subjective improvement of symptoms.

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Eye Injury

Intervention

conservative, Medical Therapy

Location

Hospital Kuala Lumpur
Kuala Lumpur
Wilayah Persekutuan
Malaysia
50586

Status

Not yet recruiting

Source

Ministry of Health, Malaysia

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:13:41-0400

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