Transplantation of Cultivated Corneal Epithelial Sheet in Patients With Ocular Surface Disease

2014-08-27 03:13:41 | BioPortfolio


The aim of the study is to assess if transplantation of cultivated corneal epithelial stem cells could restore vision in patients with severe ocular surface disorder with a favourable safety profile that warrants further comparative study.




To determine the efficacy of cultivated corneal epithelial stem cells as a treatment for patients with severe ocular surface disorder.

The corneal limbal epithelial stem cell transplant (CLET) successful outcome will be measured by improvement of vision, maintenance of corneal re-epithelisation with absence of recurrence of surface disease and subjective improvement of symptoms.

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment


Eye Injury


conservative, Medical Therapy


Hospital Kuala Lumpur
Kuala Lumpur
Wilayah Persekutuan


Not yet recruiting


Ministry of Health, Malaysia

Results (where available)

View Results


Published on BioPortfolio: 2014-08-27T03:13:41-0400

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