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Comparison of Colesevelam HCl Powder For Oral Suspension Versus Generic Cholestyramine Through Use of the Bile Acid Sequestrant Acceptability (BASA) Scale

2014-08-27 03:13:46 | BioPortfolio

Summary

The objective of this study is to compare the acceptability of Colesevelam HCl powder for oral suspension versus generic cholestyramine via the BASA scale, based upon an anticipated equivalent cholesterol lowering doses of each comparator drug.

Description

In 2009, colesevelam HCl was approved as a powder formulation. Little objective evidence exists comparing the acceptability of colesevelam HCl powder for oral suspension formulation versus other bile acid sequestrant powder formulations. A Bile Acid Sequestrant Acceptability (BASA) Scale was developed and validated as an instrument to compare the acceptability of different bile acid sequestrant preparations

Study Design

Allocation: Randomized, Endpoint Classification: Safety Study, Intervention Model: Single Group Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment

Conditions

Healthy

Intervention

Cholestyramine, Colesevelam HCl

Location

L-MARC Research Center
Louisville
Kentucky
United States
40213

Status

Active, not recruiting

Source

Louisville Metabolic and Atherosclerosis Research Center

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:13:46-0400

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