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Early Vitrectomy for Impending Macular Hole

2014-07-23 21:09:06 | BioPortfolio

Summary

This study is designed to verify hypothesis that early vitrectomy may prevent impending macular hole from progression to full-thickness macular hole.

Description

In a study conducted 15 years ago, the 'Vitrectomy for Prevention of Macular hole Study Group' was not able to prove the benefits and advantages of vitrectomy for impending macular hole; however, during the interim period, notable improvements have been achieved with regard to diagnosis and efficacy of treatment.

Therefore, we designed this study to identify the effect of current vitreous surgery for symptomatic impending macular hole.

Characteristics of this study is as below

- Multicenter, prospective clinical trial. (early surgical intervention vs.surgical intervention when full-thickness macular hole occurs)

- Non-randomized study (decision was made by patients after full explanation)

- After 1 year follow up, functional change(visual acuity)and anatomical change(development of full-thickness macular hole) would be evaluated

Study Design

Allocation: Non-Randomized, Control: Active Control, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Retinal Perforation

Intervention

Pars plana vitrectomy with ILM peeling

Location

Asan Medical Center, University of Ulsan College of Medicine
Seoul
82-2-3010-3673
Korea, Republic of
138-736

Status

Recruiting

Source

Seoul Retina Investigator Group

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-23T21:09:06-0400

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Pars Plana Vitrectomy Alone in the Treatment of Macular Schisis in High Myopic Eyes

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Anesthesia for Pars Plana Vitrectomy (PPV) With Insulin Needle

Periocular blockade with 12.5 mm needle is as effective as block with 25 mm needle for patients undergoing Pars Plana Vitrectomy.

Pars Plana Vitrectomy (PPV) Versus Preoperative Intravitreal Bevacizumab Plus PPV to Treat Diabetic Tractional Retinal Detachment (IBETRA)

The purpose of this study is to compare the amount of intraoperative intraocular bleeding during 23-gauge pars plana vitrectomy (PPV) for diabetic traction retinal detachment (TRD) with an...

The Necessity and Optimal Time for Performing Pars Plana Vitrectomy in Acute Retinal Necrosis Patients

The records of patients who were diagnosed with ARN between April 2010 and February 2017 were analyzed.A retrospective review of the treatment options and outcomes of the these patients wa...

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PubMed Articles [1342 Associated PubMed Articles listed on BioPortfolio]

Evaluation of the treatment results in patients with rhegmatogenous retinal detachment treated by pars plana vitrectomy with air: Preliminary results.

The aim of this study was to evaluate the effectiveness of treatment and the restoration of the anatomic conditions (retinal reattachment) in rhegmatogenous retinal detachment treated by pars plana vi...

Biomarkers and predictors for functional and anatomic outcomes for small gauge pars plana vitrectomy and peeling of the internal limiting membrane in naïve diabetic macular edema: The VITAL Study.

We aimed to investigate biomarkers and predictive factors for visual and anatomical outcome in patients with naïve diabetic macular edema (DME) who underwent small gauge pars plana vitrectomy (PPV) w...

OUTCOMES OF REPEAT PARS PLANA VITRECTOMY AFTER FAILED SURGERY FOR PROLIFERATIVE VITREORETINOPATHY.

To evaluate outcomes of repeat pars plana vitrectomy for proliferative vitreoretinopathy after previous failed pars plana vitrectomy.

The rate of endophthalmitis after pars plana vitrectomy and its risk factors.

To study the incidence of endophthalmitis after pars plana vitrectomy, its causative organisms, and visual acuity outcomes.

Pars Plana Vitrectomy for the Treatment of Uveitis.

To review and summarize evidence in the medical literature in regards to the use of pars plana vitrectomy in the management of uveitis.

Medical and Biotech [MESH] Definitions

Form of granulomatous uveitis occurring in the region of the pars plana. This disorder is a common condition with no detectable focal pathology. It causes fibrovascular proliferation at the inferior ora serrata.

Inflammation of the pars plana, ciliary body, and adjacent structures.

Removal of the whole or part of the vitreous body in treating endophthalmitis, diabetic retinopathy, retinal detachment, intraocular foreign bodies, and some types of glaucoma.

A region in the substantia nigra located dorsal to the PARS RETICULATA.

A region in the substantia nigra located ventral and lateral to the PARS COMPACTA.

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