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Early Vitrectomy for Impending Macular Hole

2014-07-23 21:09:06 | BioPortfolio

Summary

This study is designed to verify hypothesis that early vitrectomy may prevent impending macular hole from progression to full-thickness macular hole.

Description

In a study conducted 15 years ago, the 'Vitrectomy for Prevention of Macular hole Study Group' was not able to prove the benefits and advantages of vitrectomy for impending macular hole; however, during the interim period, notable improvements have been achieved with regard to diagnosis and efficacy of treatment.

Therefore, we designed this study to identify the effect of current vitreous surgery for symptomatic impending macular hole.

Characteristics of this study is as below

- Multicenter, prospective clinical trial. (early surgical intervention vs.surgical intervention when full-thickness macular hole occurs)

- Non-randomized study (decision was made by patients after full explanation)

- After 1 year follow up, functional change(visual acuity)and anatomical change(development of full-thickness macular hole) would be evaluated

Study Design

Allocation: Non-Randomized, Control: Active Control, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Retinal Perforation

Intervention

Pars plana vitrectomy with ILM peeling

Location

Asan Medical Center, University of Ulsan College of Medicine
Seoul
82-2-3010-3673
Korea, Republic of
138-736

Status

Recruiting

Source

Seoul Retina Investigator Group

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-23T21:09:06-0400

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PubMed Articles [1383 Associated PubMed Articles listed on BioPortfolio]

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Medical and Biotech [MESH] Definitions

Form of granulomatous uveitis occurring in the region of the pars plana. This disorder is a common condition with no detectable focal pathology. It causes fibrovascular proliferation at the inferior ora serrata.

Inflammation of the pars plana, ciliary body, and adjacent structures.

Removal of the whole or part of the vitreous body in treating endophthalmitis, diabetic retinopathy, retinal detachment, intraocular foreign bodies, and some types of glaucoma.

A region in the substantia nigra located dorsal to the PARS RETICULATA.

A region in the substantia nigra located ventral and lateral to the PARS COMPACTA.

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