Advertisement

Topics

Study Comparing Marathon Polyethylene and Enduron Polyethylene Acetabular Liners Used in Total Hip Arthroplasty

2014-08-27 03:13:47 | BioPortfolio

Summary

The purpose of the study is to determine whether crosslinked Marathon and standard Enduron polyethylene liners show differences in bone loss around the hip implant.

Description

Several institutions report very low wear rates with highly crosslinked polyethylene based on early clinical data. However, since bone loss typically appears after 5-year follow-up, the reduction in the incidence and extent of bone loss among total hip replacement patients with crosslinked Marathon liners, compared to those with standard Enduron liners, has not been as dramatic as the wear reduction. Despite the substantial reduction in wear that we observed at 5-year follow-up, the patients' perceptions of their outcomes remained similar among the Marathon and Enduron groups. This study will evaluate outcome at a minimum of 10-years after surgery among the same group of patients whose outcome was previously reported at 5-year follow-up. At 10-year follow-up, we anticipate that the reduction in wear associated with Marathon polyethylene will be associated with significant reductions in bone loss when compared to the Enduron polyethylene.

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Osteoarthritis

Intervention

Total Hip Replacement

Location

Anderson Orthopaedic Research Institute
Alexandria
Virginia
United States
22306

Status

Enrolling by invitation

Source

Anderson Orthopaedic Research Institute

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:13:47-0400

Clinical Trials [1765 Associated Clinical Trials listed on BioPortfolio]

Role of Bone in Knee Osteoarthritis (OA)

The purpose of the study is to investigate the density, architecture, and perfusion of bone marrow lesions (BMLs) in knee osteoarthritis. We will perform MRI's and QCT's on subjects prior ...

Total Knee Replacement With the Attune vs. the Press Fit Condylar (PFC) Sigma.

100 knees with primary osteoarthritis and scheduled for a total knee replacement (TKR) will be recruited from our waiting list. The patients will be randomized to become operated with the ...

Randomized Controlled Study Comparing CFP and Corail Stem

80 patients eligible for a total hip replacement (THR) mainly due to primary osteoarthritis were recruited from our waiting list. The patients were randomized to either CFP or Corail stem,...

The Postural Control in Patients After Total Hip Replacement

Total hip replacement (THR) is the procedure which can improve the quality of life in patients with osteoarthritis. However, deficits in static stability and impairment of the lower limb e...

A Trial of Mechanical Axis vs Kinematic Alignment in Total Knee Replacement

This is a prospective, randomized, longitudinal study of the clinical outcomes of osteoarthritis patients treated by two different alignment philosophies for total knee replacement. In thi...

PubMed Articles [6936 Associated PubMed Articles listed on BioPortfolio]

ACL and meniscal injuries increase the risk of primary total knee replacement for osteoarthritis: a matched case-control study using the Clinical Practice Research Datalink (CPRD).

The aim of this study was to investigate whether ACL injury (ACLi) or meniscal injury increases the risk of end-stage osteoarthritis (OA) resulting in total knee replacement (TKR).

Prospective Associations of C-Reactive Protein (CRP) Levels and CRP Genetic Risk Scores with Risk of Total Knee and Hip Replacement for Osteoarthritis in a Diverse Cohort.

To examine associations of high-sensitivity C-reactive protein (CRP) levels and polygenic CRP genetic risk scores (GRS) with risk of end-stage hip or knee osteoarthritis (OA), defined as incident tota...

A Physical Therapist-Administered Physical Activity Intervention After Total Knee Replacement: Protocol for a Randomized Controlled Trial.

The definitive treatment for knee osteoarthritis is a total knee replacement, which results in a clinically meaningful improvement in pain and physical function. However, evidence suggests that physic...

Early Clinical and Radiographic Outcomes of Trabecular Metal Total Ankle Replacement Using a Transfibular Approach.

In the last 2 decades, total ankle replacement has gained greater acceptance as a treatment option in patients with end-stage ankle osteoarthritis. However, there is a lack of literature on total ankl...

Total knee replacement and non-surgical treatment of knee osteoarthritis: 2-year outcome from two parallel randomized controlled trials.

To compare 2-year outcomes of total knee replacement (TKR) followed by non-surgical treatment to that of non-surgical treatment alone and outcomes of the same non-surgical treatment to that of written...

Medical and Biotech [MESH] Definitions

Partial or total replacement of a joint.

Partial or total replacement of one or more FINGERS, or a FINGER JOINT.

The replacement of intervertebral discs in the spinal column with artificial devices. The procedure is done in the lumbar or cervical spine to relieve severe pain resulting from INTERVERTEBRAL DISC DEGENERATION.

Partial or total replacement of the CORNEA from one human or animal to another.

Partial or total replacement of all layers of a central portion of the cornea.

More From BioPortfolio on "Study Comparing Marathon Polyethylene and Enduron Polyethylene Acetabular Liners Used in Total Hip Arthroplasty"

Advertisement
Quick Search
Advertisement
Advertisement

 

Relevant Topic

Osteoporosis
Osteoporosis is a disease in which the bones become extremely porous, are subject to fracture, and heal slowly, occurring especially in women following menopause and often leading to curvature of the spine from vertebral collapse. Follow and track&n...


Searches Linking to this Trial