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Magnetic Resonance Imaging (MRI) and Decline of Aging Aviator Performance

2014-08-27 03:13:47 | BioPortfolio

Summary

The primary purpose of this study is to apply state-of-the-art Magnetic Resonance Imaging (MRI) and Magnetic Resonance Spectroscopic Imaging (MRSI) techniques to measure changes over time in the brain.

Description

We expect that MRI and MRSI techniques will be a useful adjunct in research efforts to understand individual differences in performance of a complex attention-demanding task, such as flying a plane or driving a car. Other predictors of change in performance of a complex task may include simple tests of processing speed and working memory, past training and recent practice of the task, and genetic risk factors for degenerative brain disease. In this project, we will examine whether baseline MR measures are as useful as longitudinal MR measures in predicting amount of change over time in task performance.

This research is part of a long-term effort to achieve earlier identification of individuals at risk of decline and ultimately minimize loss of function.

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Conditions

Memory

Intervention

results of MRI scans

Location

VA Palo Alto Health Care System
Palo Alto
California
United States
94304

Status

Recruiting

Source

Stanford University

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:13:47-0400

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Medical and Biotech [MESH] Definitions

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Neurological process involving the conversion of learned information into long-term memory.

Complex mental function having four distinct phases: (1) memorizing or learning, (2) retention, (3) recall, and (4) recognition. Clinically, it is usually subdivided into immediate, recent, and remote memory.

Temporary storage of information for a few seconds to hours, as opposed to long-term memory which refers to material stored for days, years, or a lifetime.

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