Advertisement

Topics

Tissue Donation for Myoblast Culture

2014-08-27 03:13:52 | BioPortfolio

Summary

Analyze human skeletal muscle and learn more about the ability of adult muscle to produce myoblasts (young muscle cells).

Description

Study the ability of healthy human skeletal muscle to produce myoblasts, and to determine how many cells would be needed to regenerate a certain section of injured muscle. As part of this research, we hope to gain a better understanding of the effect of age on muscle and how normal skeletal muscle can regenerate itself by producing myoblasts. The information gathered from this study will be specifically used in future research for treating Anal Incontinence.

Study Design

Control: Uncontrolled, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Basic Science

Conditions

Observe in Vitro Characteristics of Muscle Tissue

Intervention

Tissue Donation

Location

UCI Women's Healthcare
Orange
California
United States
92868

Status

Active, not recruiting

Source

University of California, Irvine

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:13:52-0400

Clinical Trials [3809 Associated Clinical Trials listed on BioPortfolio]

Muscle Connective Tissue in Limb Development and Disease

The objective of this work is to understand how the disruption of the muscle connective tissue contributes to the limb soft-tissue defects in radial dysplasia. In parallel, the researchers...

Iron and Insulin Resistance in Overweight and Obese Humans

Determine the effects of reducing whole-body iron stores in overweight/obese subjects (via one-time blood donation) on adipose tissue iron content, factors regulating iron homeostasis and ...

Changes in Muscle Tissue in Patients With Pancreatic Cancer

RATIONALE: Measuring changes in muscle tissue in patients with cancer may help doctors predict how well patients will respond to treatment, and may help the study of cancer in the future. ...

Molecular, Cellular, and Genetic Characterization of Human Adipose Tissue and Its Role in Metabolism

Background: The body uses energy from calories for basic functions like breathing and digesting food. Over time, when a person eats more calories than they burn, they may become overweigh...

Osteogenic Profiling of Tissue From Children With Craniosynostosis

The primary objectives of this study are - to procure human temporalis muscle, subcutaneous adipose (fat), and bone tissue samples from children with craniosynostosis, - ...

PubMed Articles [22015 Associated PubMed Articles listed on BioPortfolio]

Bone Morphogenetic Protein-2 is a stronger inducer of osteogenesis within muscle tissue than heterodimeric Bone Morphogenetic Protein-2/6 and -2/7: implications for expedited gene-enhanced bone repair.

Bone morphogenetic protein-2 (BMP-2) gene activated muscle tissue fragments can regenerate large bone defects in preclinical animal models. The use of tissue fragments instead of isolated cells expedi...

Impact of changing the recruitment and interview procedures for cornea donation on the consent rate at a University hospital in Switzerland.

We analyzed the impact of implementing a new concept for obtaining the consent for corneal donation on donor rates at our university hospital. This study emphasizes the potential of process improvemen...

Impact of Cognitive Load on Family Decision Makers' Recall and Understanding of Donation Requests for the Genotype-Tissue Expression (GTEx) Project.

Genomic research projects that collect tissues from deceased organ and tissue donors must obtain the authorization of family decision makers under difficult circumstances that may affect the authoriza...

Crosstalk between developing vasculature and optogenetically engineered skeletal muscle improves muscle contraction and angiogenesis.

Capillary networks surrounding skeletal muscle play an important role in not only supplying oxygen and nutrients but also in regulating the myogenesis and repair of skeletal muscle tissues. Herein, we...

Effect of Cryopreservation on Human Adipose Tissue and Isolated Stromal Vascular Fraction Cells: In Vitro and In Vivo Analyses.

Adipose tissue is a source of adipose-derived stromal/stem cells for tissue engineering and reconstruction and a tissue source for fat grafts. Although liposuction is a simple procedure for the harves...

Medical and Biotech [MESH] Definitions

Tissue, organ, or gamete donation intended for a designated recipient.

Tumors or cancer located in muscle tissue or specific muscles. They are differentiated from NEOPLASMS, MUSCLE TISSUE which are neoplasms composed of skeletal, cardiac, or smooth muscle tissue, such as MYOSARCOMA or LEIOMYOMA.

Generating tissue in vitro for clinical applications, such as replacing wounded tissues or impaired organs. The use of TISSUE SCAFFOLDING enables the generation of complex multi-layered tissues and tissue structures.

A technique for maintaining or growing TISSUE in vitro, usually by DIFFUSION, perifusion, or PERFUSION. The tissue is cultured directly after removal from the host without being dispersed for cell culture.

Injuries of tissue other than bone. The concept is usually general and does not customarily refer to internal organs or viscera. It is meaningful with reference to regions or organs where soft tissue (muscle, fat, skin) should be differentiated from bones or bone tissue, as "soft tissue injuries of the hand".

More From BioPortfolio on "Tissue Donation for Myoblast Culture"

Advertisement
Quick Search
Advertisement
Advertisement

 

Relevant Topics

Rheumatology
Arthritis Fibromyalgia Gout Lupus Rheumatic Rheumatology is the medical specialty concerned with the diagnosis and management of disease involving joints, tendons, muscles, ligaments and associated structures (Oxford Medical Diction...

Nutrition
Within medicine, nutrition (the study of food and the effect of its components on the body) has many different roles. Appropriate nutrition can help prevent certain diseases, or treat others. In critically ill patients, artificial feeding by tubes need t...

Urology
Benign Prostatic Hyperplasia (BPH) Erectile Dysfunction Urology Urology is the branch of medicine concerned with the urinary tract and diseases that affect it. Examples include urethritis, urethrostenosis and incontinence. Urology is a su...


Searches Linking to this Trial