Advertisement

Topics

Effects of Vagus Nerve Stimulation (VNS) as a Treatment of Persistent Depression With Comorbid Personality Disorders (Impulse-VNS

2014-08-27 03:13:53 | BioPortfolio

Summary

In this monocentre two-armed double blind randomised placebo-controlled study - in which the control group obtains the VNS therapy within a defined space of time after 12 weeks - the impact of vagus nerve stimulation on depressive symptomatology of patients with therapy-resistant depressive personality disorders shall be analysed. Particularly in comorbid disorders, medicamentous treatment shows exceedingly bad response rates. Against the background of hitherto insufficient treatment strategies for chronic or persistent depression with comorbidities, the proceeding of a study on the effects of VNS on depressive patients with comorbid disorders is absolutely essential.

Study Design

Allocation: Randomized, Control: Active Control, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment

Conditions

Depression

Intervention

VNS Pulse Model 102, VNS Pulse Model 102

Location

Dept. of Psychiatry and Psychotherapy (University Medical Centre)
Goettingen
Niedersachsen
Germany
37075

Status

Recruiting

Source

University Medical Center Goettingen

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:13:53-0400

Clinical Trials [3175 Associated Clinical Trials listed on BioPortfolio]

Comparison of Pulse Chips and Commercial Snacks on Food Intake, Appetite and Blood Glucose in Healthy Young Adults

Consumers are often forced to eat fast, convenient foods and snacks ("eat on the go") in order to match the pace of their lifestyles. However, these snack options more often than not offer...

Oxitone Sp02 Hypoxia Test Versus Reference Pulse Oximetry

The purpose of this study is to conduct a SpO2 hypoxia evaluation of the Oxitone Medical Oxitone 1000 pulse oximeter. The Oxitone 1000 pulse oximeter will be evaluated during non-motion co...

Study on Changes of Pulse Oximeter Plethysmographic Amplitude Induced by Respiration in Pediatric Patients

The purpose of this study is to evaluate the variations of respiratory changes in pulse oximeter plethysmographic amplitude (delta POP) according to different contact forces between finger...

Accuracy of Pulse Oximeters With Profound Hypoxia

The aim of this project is to test the accuracy of pulse oximeters during mild, moderate and severe hypoxia. This is done by comparing the reading of the pulse oximeter during brief, stead...

Fetal Pulse Oximetry Trial (FOX)

The purpose of this study is to determine if the information provided to the physician by a fetal pulse oximeter during labor will reduce the chances of a cesarean delivery.

PubMed Articles [21400 Associated PubMed Articles listed on BioPortfolio]

EVIDENCE THAT DYNORPHIN ACTS UPON KNDy AND GnRH NEURONS DURING GnRH PULSE TERMINATION IN THE EWE.

A subpopulation of neurons located within the arcuate nucleus, co-localizing kisspeptin, neurokinin B, and dynorphin, (termed KNDy neurons) are key mediators of pulsatile gonadotropin-releasing hormon...

Accuracy of Smartphone-Based Pulse Oximetry Compared with Hospital-Grade Pulse Oximetry in Healthy Children.

Pulse oximetry, a ubiquitous, noninvasive method to monitor oxygen saturation (SpO2), requires larger, nonportable equipment. Smartphone pulse oximeter applications (apps) provide a portable, cost-eff...

Electrosorption enhanced electrooxidation of a model organic pollutant at 3D SnO2-Sb electrode in superimposed pulse current mode.

In this work, the novel pulse "electrosorption-electrooxidation-electrosorption" (PESO) mode is developed in the superimposed pulse current system for benzoic acid oxidation. Due to the synergistic ef...

Pulse stretcher with two beamsplitting elements for excimer laser pulses.

A pulse stretcher with two beamsplitting elements and an optical ring cavity is proposed. With a two-beamsplitting-element configuration, the temporal profile of the stretched output pulse is effectiv...

Dynamics of Cholera Epidemics with Impulsive Vaccination and Disinfection.

Waterborne diseases have a tremendous influence on human life. The contaminated drinking water causes water-borne disease like cholera. Pulse vaccination is an important and effective strategy for the...

Medical and Biotech [MESH] Definitions

Use of a pulse of X-rays or fast electrons to generate free radicals for spectroscopic examination.

Statistical formulations or analyses which, when applied to data and found to fit the data, are then used to verify the assumptions and parameters used in the analysis. Examples of statistical models are the linear model, binomial model, polynomial model, two-parameter model, etc.

Evaluation of the contour of the PULSE waves which vary in different parts of the circulation and depend on physiological as well as pathophysiological conditions of the individual.

Technique used in AYURVEDIC MEDICINE, and EAST ASIAN TRADITIONAL MEDICINE, in which reading PULSE is used in the diagnosis of diseases.

Theoretical models simulating behavior or activities in nursing, including nursing care, management and economics, theory, assessment, research, and education. Some examples of these models include Orem Self-Care Model, Roy Adaptation Model, and Rogers Life Process Model.

More From BioPortfolio on "Effects of Vagus Nerve Stimulation (VNS) as a Treatment of Persistent Depression With Comorbid Personality Disorders (Impulse-VNS"

Advertisement
Quick Search
Advertisement
Advertisement

 

Relevant Topic

Bipolar Disorders
Bipolar disorder, also known as manic-depressive illness, is a brain disorder that causes unusual shifts in mood, energy, activity levels, and the ability to carry out day-to-day tasks. Over half of Bipolar cases develops before the age of 25. Bipolar ...


Searches Linking to this Trial