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Intrarectal Misoprostol in Postpartum Haemorrhage

2014-08-27 03:13:59 | BioPortfolio

Summary

Postpartum haemorrhage (PPH) remains the major cause of maternal mortality in France. The most efficient treatment of severe PPH is sulprostone which is associated with cardiac complications. The objective of this study was to assess the efficacy and the safety of intrarectal misoprostol for curative postpartum haemorrhage treatment.

We conducted a multicenter double blind randomized placebo control trial between June 2004 and December 2007, among consenting women with postpartum haemorrhage and failure to oxytocin treatment.

Our main criteria of judgement was quantification of blood loss and the use of sulprostone between the two groups using either misoprostol intrarectal tablets (5X200mg ) or placebo in similar opaque introducer.

Study Design

Primary Purpose: Treatment

Conditions

Postpartum Haemorrhage

Intervention

Misoprostol, Placebo

Status

Completed

Source

University Hospital, Caen

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:13:59-0400

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