Frovatriptan and Menstrual Migraine

2014-08-27 03:14:01 | BioPortfolio


We are looking for women who suffer from menstrual migraine to participate in a 2-visit migraine brain imaging research study. Our goal is to see how the menstrual migraine brain's pain pathways function when the migraineur has been taking Frovatriptan. During the screening visit (Visit 1) participants will sign the informed consent form, complete questionnaires, meet with the study physician, and have QST (quantitative sensory testing: to determine your pain thresholds for a heat stimulus) performed. For Visit 2's MRI scan, subjects will be asked to lie very still while the scan is occurring. In some parts, they will not have to do anything, while in others they will be asked to rate pain and unpleasantness for brush and thermal stimuli. Participants are compensated for both visits.

Study Design

Observational Model: Cohort




Neuroimaging Center, McLean Hospital
United States




Mclean Hospital

Results (where available)

View Results


Published on BioPortfolio: 2014-08-27T03:14:01-0400

Clinical Trials [5 Associated Clinical Trials listed on BioPortfolio]

A Controlled Trial to Investigate the Efficacy and Safety of Frovatriptan to Prevent Menstrual Migraine

Although the predictability of an MRM headache attack lends itself to preventative treatment, there are currently no drugs specifically indicated for the prevention of MM. Such preventativ...

A Randomized Trial of Frovatriptan for the Intermittent Prevention of Menstrual Migraine

The primary objective of this study was to determine whether frovatriptan was effective in the prevention of menstrually associated migraine (MAM) headaches when compared to placebo. Secon...

Frovatriptan as a Transitional Therapy in Medication Overuse Headache

This study will analyze the effectiveness of a medication called Frovatriptan, in the context of medication overuse headache (MOH). MOH is a headache that develops when pain-killers are t...

Prevention of Menstrual Migraines: Using Frovatriptan or Placebo During Hormone Free Intervals

This study will examine the combined effects of a continuous oral contraceptive (OC) regimen with supplemental frovatriptan therapy on headache severity and occurrence in subjects with doc...

A Research Study To Evaluate If Frovatriptan Is Safe And Effective In Preventing Migraine Headache After Fasting

We are testing the hypothesis that subjects in the treatment group will experience fewer fasting induced headaches as compared to those in the placebo group.In our clinical experience, we ...

PubMed Articles [1 Associated PubMed Articles listed on BioPortfolio]

Intranasal Drug Delivery of Frovatriptan Succinate Loaded Polymeric Nanoparticles for Brain Targeting.

The objective of present study was to develop polymeric nanoparticles (PNPs) of Frovatriptan Succinate (FS) for brain targeting by nasal route. Double emulsion method was used to increase the entrapme...

Medical and Biotech [MESH] Definitions

None available.

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