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Characterization Phenotypic and Genetic Study of the Intestinal Epithelial Dysplasia or Tufting Enteropathy (TE)

2014-08-27 03:14:05 | BioPortfolio

Summary

This PHRC is centred on the intestinal epithelial dysplasia ( DEI) or " tufting enteropathy " or TE the clinical and histo-pathological descriptions of which are specified well to the digestive plan(shot).

Description

The objectives of this PHRC are:

- the phenotypic analysis of the intestinal epithelial dysplasia by clinical and histo-pathological investigations.

- the identification of proteins involved at the intestinal level in the differentiation, the proliferation and the membership of the epithelial cells

- from the phenotypic study, a genetic analysis of type maps by homozygote on the whole genome partner in an approach guided by possible candidate genes

- the study of the genes, chosen according to their location, to their profile of expression, and to their function in touch with the pathogenic hypotheses

Study Design

Allocation: Non-Randomized, Control: Historical Control, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Diagnostic

Conditions

Intestinal Epithelial Dysplasia

Intervention

blood samples and skin biopsies, Skin biopsies

Location

Necker Hospital
Paris
France
75015

Status

Recruiting

Source

Assistance Publique - Hôpitaux de Paris

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:14:05-0400

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