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Omega-3 and Aspirin in Periodontal Regeneration

2014-08-27 03:14:05 | BioPortfolio

Summary

To evaluate the efficacy of systemic administration of omega 3 PUFA plus low dose aspirin as an adjunctive therapy to regenerative modality of grade II furcation defects in periodontitis patients.

Description

In this study, we tested the hypothesis that the administration of omega 3 PUFA plus low dose aspirin would augment the results following regenerative therapy of furcation defects in chronic periodontitis patients.

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment

Conditions

Periodontal Disease

Intervention

Regenerative therapy (omega 3 PUFA plus low dose aspirin), Sugar pill

Location

October 6 University
Cairo
Overnorate of 6 October
Egypt
part 1/1

Status

Completed

Source

October 6 University

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:14:05-0400

Clinical Trials [1137 Associated Clinical Trials listed on BioPortfolio]

Effects of Omega-3 Plus Low-dose Aspirin as Adjunct to Periodontal Debridement for Chronic Periodontitis in Diabetics

Therefore, the aim of this study is to investigate the effectiveness of daily supplementation of omega-3 polyunsaturated fatty acids and low-dose aspirin as adjunct therapy to one-stage fu...

Omega-3 Plus Low-dose Aspirin Daily Supplementation in Non-surgical Therapy to Treat Aggressive Periodontitis

The aim of this randomized controlled clinical trial of superiority will be to evaluate the effect of 900 mg of omega-3 polyunsaturated fatty acids and 100 mg of aspirin daily supplementat...

Omega-3 Fatty Acids Plus Low-dose Aspirin Daily Supplementation in Surgical Therapy to Treat Aggressive Periodontitis

The aim of this randomized controlled clinical trial of superiority will be to evaluate the effect of 900 mg of omega-3 polyunsaturated fatty acids and 100 mg of aspirin daily supplementat...

Study of the Implication of Omega-3 Polyunsaturated Fatty Acids in Retinopathy of Prematurity in New-born Infants

The development of the retinal vascular network is generally complete during the 3rd trimester of pregnancy but may continue during the first 15 days of life. This late maturation may caus...

Preoperative Carbohydrate Load and Intraoperative w3-PUFA in CAGB Surgery

Omega-3 polyunsaturated fatty acids (w-3-PUFA) may have a potential role in enhance the postoperative balance of host immunity and reduce the incidence of postoperative atrial fibrillation...

PubMed Articles [13960 Associated PubMed Articles listed on BioPortfolio]

The Role of Aspirin and Unfractionated Heparin Combination Therapy Immediately After Total Hip and Knee Arthroplasty.

Aspirin and unfractionated heparin (UH) are accepted options for venous thromboembolism (VTE) prophylaxis after total joint arthroplasty (TJA). The use of aspirin in addition to UH in preventing VTE a...

Treatment with omega-3 polyunsaturated fatty acids does not improve endothelial function in patients with type 2 diabetes and very high cardiovascular risk: A randomized, double-blind, placebo-controlled study (Omega-FMD).

Numerous recent studies conducted in different clinical settings have focused on the benefits of omega-3 polyunsaturated fatty acids (n-3 PUFAs) in the prevention of cardiovascular diseases. There is ...

Low dose aspirin is associated with reduced spontaneous preterm birth in nulliparous women.

Preterm birth (PTB) is one of the leading causes of perinatal morbidity and mortality. Clinical data suggests that low dose aspirin may decrease the rate of overall PTB, but investigators have specula...

Duration of high-dose aspirin therapy does not affect long-term coronary artery outcomes in kawasaki disease.

High-dose aspirin (HDA) is used with intravenous immunoglobulin (IVIg) in Kawasaki Disease (KD). Practice regarding HDA varies, and it is unclear whether HDA duration affects long-term course.

Omega-3 Fatty Acids and Insulin Resistance: Focus on the Regulation of Mitochondria and Endoplasmic Reticulum Stress.

Mitochondrial dysfunction and endoplasmic reticulum (ER) stress have been suggested to play a key role in insulin resistance development. Reactive oxygen species (ROS) production and lipid accumulatio...

Medical and Biotech [MESH] Definitions

FATTY ACIDS which have the first unsaturated bond in the sixth position from the omega carbon. A typical American diet tends to contain substantially more omega-6 than OMEGA-3 FATTY ACIDS.

A non-steroidal anti-inflammatory agent that is less effective than equal doses of ASPIRIN in relieving pain and reducing fever. However, individuals who are hypersensitive to ASPIRIN may tolerate sodium salicylate. In general, this salicylate produces the same adverse reactions as ASPIRIN, but there is less occult gastrointestinal bleeding. (From AMA Drug Evaluations Annual, 1992, p120)

Asthmatic adverse reaction (e.g., BRONCHOCONSTRICTION) to conventional NSAIDS including aspirin use.

The dose amount of poisonous or toxic substance or dose of ionizing radiation required to kill 50% of the tested population.

A drug combination of aspirin and dipyridamole that functions as a PLATELET AGGREGATION INHIBITOR, used to prevent THROMBOSIS and STROKE in TRANSIENT ISCHEMIC ATTACK patients.

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