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Hypertonic Saline (6%) Versus Isotonic Saline (0.9%) in Bronchiectasis

2014-08-27 03:14:06 | BioPortfolio

Summary

The investigators hypothesise that nebulised hypertonic saline (6%) will increase the volume of sputum expectorated over a 24 hour period compared to nebulised isotonic saline (0.9%) in patients with mild to severe stable bronchiectasis.

Study Design

Allocation: Randomized, Control: Placebo Control, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment

Conditions

Bronchiectasis

Intervention

Hypertonic saline, Isotonic saline

Location

Belfast HSCT
Belfast
Northern Ireland
United Kingdom
BT9 7AB

Status

Recruiting

Source

Belfast Health and Social Care Trust

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:14:06-0400

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PubMed Articles [781 Associated PubMed Articles listed on BioPortfolio]

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Medical and Biotech [MESH] Definitions

Hypertonic sodium chloride solution. A solution having an osmotic pressure greater than that of physiologic salt solution (0.9 g NaCl in 100 ml purified water).

A genus of HALOBACTERIACEAE distinguished from other genera in the family by the presence of specific derivatives of TGD-2 polar lipids. Haloarcula are found in neutral saline environments such as salt lakes, marine salterns, and saline soils.

A family of gram-negative, moderately halophilic bacteria in the order Oceanospirillales. Members of the family have been isolated from temperate and Antarctic saline lakes, solar salt facilities, saline soils, and marine environments.

A species of PERCIFORMES commonly used in saline aquaculture.

Water from natural sources which contain significant concentrations of dissolved salts such as sodium chloride.

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