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Temsirolimus in Myelodysplastic Syndrome (MDS)

2014-07-24 14:05:57 | BioPortfolio

Summary

The goal of this Pilot-study is to evaluate the response of unselected MDS patients to temsirolimus a drug approved for the treatment of renal cell cancer. It is planned to give temsirolimus at a weekly dose of 25 mg as intravenous infusion for a maximum duration of 12 months. Regular bone marrow biopsies are planned for controlling MDS response.

Study Design

Allocation: Non-Randomized, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Myelodysplastic Syndrome

Intervention

Temsirolimus

Location

Klinikum Chemnitz Klinik für Innere Medizin III
Chemnitz
Germany
09113

Status

Recruiting

Source

Dresden University of Technology

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-24T14:05:57-0400

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PubMed Articles [4739 Associated PubMed Articles listed on BioPortfolio]

Clonal cytogenetic abnormalities of undetermined significance.

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Targeted Next-Generation Sequencing Is a Sensitive Tool for Differential Diagnosis of Myelodysplastic Syndromes in Bone Marrow Trephines.

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Medical and Biotech [MESH] Definitions

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