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Transoral Incisionless Fundoplication (TIF) Versus Sham for Treatment of Gastroesophageal Reflux Disease (GERD)

2014-07-23 21:09:26 | BioPortfolio

Summary

The study objective is to evaluate the relative merits, safety and effectiveness of transoral incisionless fundoplication (TIF) in proton pump inhibitor (PPI) dependent GERD patients compared with sham procedure.

Study Design

Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment

Conditions

Gastroesophageal Reflux Disease

Intervention

Transoral Incisionless Fundoplication (TIF)

Location

University Hospitals Leuven
Leuven
Belgium

Status

Recruiting

Source

EndoGastric Solutions

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-23T21:09:26-0400

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PubMed Articles [14530 Associated PubMed Articles listed on BioPortfolio]

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Medical and Biotech [MESH] Definitions

Mobilization of the lower end of the esophagus and plication of the fundus of the stomach around it (fundic wrapping) in the treatment of GASTROESOPHAGEAL REFLUX that may be associated with various disorders, such as hiatal hernia. (From Dorland, 28th ed)

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Back flow of gastric contents to the LARYNGOPHARYNX where it comes in contact with tissues of the upper aerodigestive tract. Laryngopharyngeal reflux is an extraesophageal manifestation of GASTROESOPHAGEAL REFLUX.

The R-isomer of lansoprazole that is used to treat severe GASTROESOPHAGEAL REFLUX DISEASE.

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