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A Comparison of Oxycodone/Naloxone and Oxycodone After Laparoscopic Hysterectomy

2014-07-23 21:09:27 | BioPortfolio

Summary

Objectives:

Primary objective:

- To demonstrate that the treatment with OXN PR tablets up to 72 hrs after surgery is superior to the treatment with OxyPR with regards to constipation in subjects with postoperative pain after laparoscopic hysterectomy based on interviews 24h, 72 h and 1 week postoperatively.

The secondary objectives:

- Analgesic effect (including registration during the first 24 hrs)

- To asses the frequency of pain rescue mediation use (in the double-blind phase, 0-72 hrs)

- Frequency of nausea and vomiting

- Frequency of other adverse events

- Appetite

- Mobilization

The exploratory objectives:

- Overall patient satisfaction at 24, 72 hrs and 1 week

Study Design

N/A

Conditions

Postoperative Pain

Intervention

naloxone, oxycodone

Location

Dept of Anesthesiology, Oslo University Hospital, Ullevaal
Oslo
Norway
0407

Status

Recruiting

Source

Ullevaal University Hospital

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-23T21:09:27-0400

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Anesthesiology
An anesthesiologist (US English) or anaesthetist (British English) is a physician trained in anesthesia and perioperative medicine. Anesthesiologists are physicians who provide medical care to patients in a wide variety of (usually acute) situations. ...


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