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LOC387715/HTRA1 Variants in Polypoidal Choroidal Vasculopathy in a Korean Population

2014-08-27 03:14:26 | BioPortfolio

Summary

This study is to investigate whether variants in the LOC387715 locus and the HtrA serine peptidase 1 (HTRA1) gene within the 10q26 locus are associated with polypoidal choroidal vasculopathy and whether they are associated with clinical patterns including angiographic phenotype in a Korean population.

Description

This is a cross-sectional case-control study. One hundred Korean patients with polypoidal choroidal vasculopathy and 100 control subjects were genotyped for the LOC387715 (rs10490924) and the HTRA1 gene polymorphism (rs11200638)

Study Design

Allocation: Non-Randomized, Control: Historical Control, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Basic Science

Conditions

Age-Related Macular Degeneration

Intervention

LOC387715/HTRA1 genotyping

Location

In Taek Kim
Daegu
Kyungsangpookdo
Korea, Republic of
700-721

Status

Recruiting

Source

Kyungpook National University

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:14:26-0400

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