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Assess the Blood-Oxygen-Level-Dependent (BOLD) Signal Changes in the Brain by Paracetamol as Measured by Functional Magnetic Resonance Imaging (fMRI) in Subjects With Osteoarthritis (OA)

2014-08-27 03:14:32 | BioPortfolio

Summary

Blood-Oxygen-Level-Dependent (BOLD) functional Magnetic Resonance Imaging (fMRI) responses to painful mechanical stimulation of the OA knee following treatment with four consecutive doses (at 8 hour intervals) of a sustained released paracetamol treatment or placebo. The fMRI and pain assessments will occur approximately 2-5 hours after taking the final dose.

Study Design

Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Basic Science

Conditions

Osteoarthritis, Knee

Intervention

No treatment, Paracetamol, Placebo

Location

GSK Investigational Site
Barcelona
Spain

Status

Not yet recruiting

Source

GlaxoSmithKline

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:14:32-0400

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