Dengue Seroprevalence Study in Blood Donors in the French West Indies
Summary
Dengue is an infectious disease most prevalent in the world. This disease is endemic in the Caribbean, with an increase in seasonal rains. Several outbreaks have been observed in recent years, in 2001, 2005 and 2007, during which further particularly virulent serotypes have emerged. The clinical expression of dengue fever is variable, ranging from no symptoms to a classical form with fever, and even of severe or lethal bleeding. With the possible existence of silent forms of the disease, there are no data identifying the current level of protection of the population in Martinique / Guadeloupe.
Description
1. Principal objective:
To estimate the prevalence of the specific antibodies of the dengue (IgG) in blood donors in the French West Indies.
2. Secondary objective:
To specify the serotypic specificity of the anti-dengue antibodies detected during the study.
Study Design
Observational Model: Cohort, Time Perspective: Prospective
Conditions
Blood Donors
Intervention
Biological sample collection
Location
French Blood Establishment of Guadeloupe
Pointe-à-Pitre
Guadeloupe
97171
Status
Not yet recruiting
Source
Etablissement Français du Sang, Martinique
Results (where available)
Links
- Source: http://clinicaltrials.gov/show/NCT01104740
- Information obtained from ClinicalTrials.gov on July 15, 2010
Published on BioPortfolio: 2014-08-27T03:14:33-0400
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Medical and Biotech [MESH] Definitions
Blood Specimen Collection
The taking of a blood sample to determine its character as a whole, to identify levels of its component cells, chemicals, gases, or other constituents, to perform pathological examination, etc.
Microscopy, Scanning Tunneling
A type of scanning probe microscopy in which a very sharp conducting needle is swept just a few angstroms above the surface of a sample. The tiny tunneling current that flows between the sample and the needle tip is measured, and from this are produced three-dimensional topographs. Due to the poor electron conductivity of most biological samples, thin metal coatings are deposited on the sample.
Donor Selection
The procedure established to evaluate the health status and risk factors of the potential DONORS of biological materials. Donors are selected based on the principles that their health will not be compromised in the process, and the donated materials, such as TISSUES or organs, are safe for reuse in the recipients.
Blood Safety
The degree to which the blood supply for BLOOD TRANSFUSIONS is free of harmful substances or infectious agents, and properly typed and crossmatched (BLOOD GROUPING AND CROSSMATCHING) to insure serological compatibility between BLOOD DONORS and recipients.
Library Collection Development
Development of a library collection, including the determination and coordination of selection policy, assessment of needs of users and potential users, collection use studies, collection evaluation, identification of collection needs, selection of materials, planning for resource sharing, collection maintenance and weeding, and budgeting.
