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Preventive Effect of the PRetreatment With Intravenous Nicorandil on Contrast-Induced Nephropathy in Patients With RenaL Dysfunction UndEergoing Coronary Angiography (PRINCIPLE Study)

2014-08-27 03:14:34 | BioPortfolio

Summary

Renal hypoxia plays an important role in the development of contrast-induced nephropathy. The purpose of the PRINCIPLE study is to investigate the effect of pretreatment with intravenous nicorandil on the incidence of contrast-induced nephropathy in patients with renal insufficiency undergoing coronary angiography.

Study Design

Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention

Conditions

Chronic Renal Failure

Intervention

pretreatment with intravenous nicorandil vs. placebo before coronary angiography

Location

Severance Hospital
Seoul
Korea, Republic of
120-752

Status

Not yet recruiting

Source

Yonsei University

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:14:34-0400

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