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The aim of Alizé is to describe a population of premature babies (gestational age, birth clinical characteristics and particularly the respiratory function) with a gestational age (GA) < 32 weeks in real life, under a treatment with prophylactic Curosurf.
Other objectives are the evaluation of the mother prenatal corticosteroids treatment for a prophylaxis of the neonatal RDS, the mother medical and obstetric history, the description of the premature babies care in the delivery suite with a special focus on the Curosurf use.
Observational Model: Cohort, Time Perspective: Prospective
Respiratory Distress Syndrome, Newborn
Laboratoire Chiesi S.A.
Chiesi Farmaceutici S.p.A.
Published on BioPortfolio: 2014-07-23T21:09:34-0400
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A chronic lung disease developed after OXYGEN INHALATION THERAPY or mechanical ventilation (VENTILATION, MECHANICAL) usually occurring in certain premature infants (INFANT, PREMATURE) or newborn infants with respiratory distress syndrome (RESPIRATORY DISTRESS SYNDROME, NEWBORN). Histologically, it is characterized by the unusual abnormalities of the bronchioles, such as METAPLASIA, decrease in alveolar number, and formation of CYSTS.
A condition of the newborn marked by DYSPNEA with CYANOSIS, heralded by such prodromal signs as dilatation of the alae nasi, expiratory grunt, and retraction of the suprasternal notch or costal margins, mostly frequently occurring in premature infants, children of diabetic mothers, and infants delivered by cesarean section, and sometimes with no apparent predisposing cause.
A respiratory distress syndrome in newborn infants, usually premature infants with insufficient PULMONARY SURFACTANTS. The disease is characterized by the formation of a HYALINE-like membrane lining the terminal respiratory airspaces (PULMONARY ALVEOLI) and subsequent collapse of the lung (PULMONARY ATELECTASIS).
A syndrome characterized by progressive life-threatening RESPIRATORY INSUFFICIENCY in the absence of known LUNG DISEASES, usually following a systemic insult such as surgery or major TRAUMA.
A syndrome characterized by outbreaks of late term abortions, high numbers of stillbirths and mummified or weak newborn piglets, and respiratory disease in young unweaned and weaned pigs. It is caused by PORCINE RESPIRATORY AND REPRODUCTIVE SYNDROME VIRUS. (Radostits et al., Veterinary Medicine, 8th ed, p1048)
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