Advertisement

Topics

Gene Expression Profiles in Healing and Non-Healing Wound

2014-07-23 21:09:34 | BioPortfolio

Summary

The purpose of the research is to determine whether there are similar patterns of genes being turned on and/or turned off among people with healing and non-healing wounds.

Description

A single subject will provide 2 tissue samples from a single wound over a 4 week time period and the samples will be categorized as healing versus non-healing responses on the basis of decreased (healing) or increased (non-healing) wound area measurements over the 4-week time period. A chronic wound generally is a wound which shows no signs of significant healing in four weeks or has not healed in eight weeks.

Study Design

Observational Model: Case-Only, Time Perspective: Prospective

Conditions

Wounds and Injuries

Location

Comprehensive Wound Center, The Ohio State University Medical Center.
Columbus
Ohio
United States
43221

Status

Recruiting

Source

Ohio State University

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-23T21:09:34-0400

Clinical Trials [396 Associated Clinical Trials listed on BioPortfolio]

Study to Evaluate Polyheal-1 in Treatment of Recalcitrant Wounds

The objective of this study is to evaluate the performance of Polyheal-1 compared to Saline in the treatment of recalcitrant wounds including venous, post-operative and post-traumatic chro...

Outcome for Patients With War-Associated Extremity Wound Infection

Extremity wounds and fractures constitute the majority of war-associated traumatic injuries, both for civilians and combatants. War-associated injuries are often contaminated with foreign ...

DURAFIBER Ag Post-Market Clinical Follow-Up

The aim of the study is to evaluate the performance of DURAFIBER Ag and to assess how many bacteria are present in infected wounds over an 8 week period.

A Trial of Topical Aloe Vera Gel in Emergency Department Patients Presenting With Simple Traumatic Wounds

This is a double blind placebo-controlled RCT comparing the speed of healing of simple traumatic wounds with Aloe Vera gel compared to both control (Ultrasound gel) and standard care.

Gene Therapy to Improve Wound Healing in Patients With Diabetes

Patients with diabetes may develop chronic wounds that respond poorly to treatment. Gene therapy with the platelet-derived growth factor-B gene has been shown to help with the healing of ...

PubMed Articles [1662 Associated PubMed Articles listed on BioPortfolio]

Study of Radial Nerve Injury Caused By Gunshot Wounds and Explosive Injuries among Iraqi Soldiers.

Gunshot wounds and blast injuries to the upper limbs produce complex wounds requiring management by multiple surgical specialities.

Changes in the Biomechanical Properties of Human Skin in Hyperthermic and Hypothermic Ranges.

The prevalence of thermal skin injuries is high. Despite new research findings, skin burns and acute cold-contact injuries, together with resulting tissue damage, are not entirely understood. In parti...

Application of the injury scales in homicides.

Injury scales have two main applications on homicide investigations, namely, to evaluate the severity of the victims' injuries and to identify the profiles of the offenders. However, few studies have ...

Wartime Soft Tissue Coverage Techniques for the Deployed Surgeon.

Since the start of the conflict in the Middle East in 2001, military orthopedic surgeons have faced complex orthopedic injuries including high-energy soft tissue wounds, traumatic amputations, and ope...

The spectrum of injuries resulting from abdominal stab wounds with isolated omental evisceration: A South African experience.

The spectrum of injury associated with anterior abdominal stab wounds (SWs) is well established. The literature in the specific setting of isolated omental evisceration is limited.

Medical and Biotech [MESH] Definitions

Head injuries which feature compromise of the skull and dura mater. These may result from gunshot wounds (WOUNDS, GUNSHOT), stab wounds (WOUNDS, STAB), and other forms of trauma.

WOUNDS and INJURIES and PSYCHOLOGICAL TRAUMA sustained during WAR.

Penetrating stab wounds caused by needles. They are of special concern to health care workers since such injuries put them at risk for developing infectious disease.

Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).

Injuries caused by impact with a blunt object where there is no penetration of the skin.

More From BioPortfolio on "Gene Expression Profiles in Healing and Non-Healing Wound"

Advertisement
Quick Search
Advertisement
Advertisement

 

Relevant Topic

Wound management
Anything that breaks the skin is a wound because when the skin is broken, there's a risk of germs getting into the body and causing an infection. Follow and track Wound Care News on BioPortfolio: Wound Car...


Searches Linking to this Trial