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Vimpat® Added as Adjunctive Therapy to One Baseline Antiepileptic Drug

2014-07-23 21:09:39 | BioPortfolio

Summary

The purpose of this study is to systematically and prospectively collect data from patients with partial-onset seizures in routine clinical practice setting receiving adjunctive Vimpat®. The observed population will be only patients with one baseline antiepileptic drug. Seizure control and tolerability data will be evaluated.

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Conditions

Epilepsies, Partial

Location

Aachen
Germany

Status

Enrolling by invitation

Source

UCB, Inc.

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-07-23T21:09:39-0400

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Medical and Biotech [MESH] Definitions

Conditions characterized by recurrent paroxysmal neuronal discharges which arise from a focal region of the brain. Partial seizures are divided into simple and complex, depending on whether consciousness is unaltered (simple partial seizure) or disturbed (complex partial seizure). Both types may feature a wide variety of motor, sensory, and autonomic symptoms. Partial seizures may be classified by associated clinical features or anatomic location of the seizure focus. A secondary generalized seizure refers to a partial seizure that spreads to involve the brain diffusely. (From Adams et al., Principles of Neurology, 6th ed, pp317)

A disorder characterized by recurrent focal onset seizures which have sensory (i.e., olfactory, visual, tactile, gustatory, or auditory) manifestations. Partial seizures that feature alterations of consciousness are referred to as complex partial seizures (EPILEPSY, COMPLEX PARTIAL).

A partial denture constructed before the teeth it replaces are removed. It is then inserted immediately after the removal of the natural teeth for functional and cosmetic reasons during the healing process. It is to be replaced later by the fitted partial denture.

A disorder characterized by recurrent partial seizures marked by impairment of cognition. During the seizure the individual may experience a wide variety of psychic phenomenon including formed hallucinations, illusions, deja vu, intense emotional feelings, confusion, and spatial disorientation. Focal motor activity, sensory alterations and AUTOMATISM may also occur. Complex partial seizures often originate from foci in one or both temporal lobes. The etiology may be idiopathic (cryptogenic partial complex epilepsy) or occur as a secondary manifestation of a focal cortical lesion (symptomatic partial complex epilepsy). (From Adams et al., Principles of Neurology, 6th ed, pp317-8)

A partial denture attached to prepared natural teeth, roots, or implants by cementation.

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