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Radiofrequency Versus Laser Ablation for Hepatocellular Carcinoma

2014-08-27 03:14:51 | BioPortfolio

Summary

The purpose of this study is to prospectively compare percutaneous radiofrequency ablation (RFA) versus percutaneous laser ablation (LA) for the treatment of small hepatocellular carcinoma in patients with cirrhosis.

Description

Percutaneous ablation is a safe and effective therapy for cirrhotic patients with HCC when resection or liver transplantation is not possible. Among the various percutaneous local ablative therapies, radiofrequency ablation (RFA) has attracted the greatest interest because of its effectiveness and safety for single HCC ≤ 5.0cm or ≤3 HCC nodules ≤3cm. Some studies have shown that laser ablation (LA) may be as effective as RFA in the treatment of HCC. However, RFA and LA are different techniques and, in different cases (for example: size or site of HCC nodule), each of these procedures may have some advantages or disadvantages. Therefore there is the need for a prospective randomized controlled study to compare RFA and LA in patients with small HCC.

Study Design

Allocation: Randomized, Control: Active Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Carcinoma, Hepatocellular

Intervention

percutaneous radiofrequency ablation, percutaneous laser ablation

Location

Liver Unit - Cardarelli Hospital
Naples
Italy
80131

Status

Recruiting

Source

Cardarelli Hospital

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:14:51-0400

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