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Background: Occupational exposures are thought to be responsible for 10-15% of new-onset asthma cases in adults, with disparities across sectors. Because most of the data are derived from registries and cross-sectional studies, little is known about incidence of occupational asthma (OA) during the first years after inception of exposure. This study focuses on this early asthma onset period among young workers in the bakery, pastry making and hairdressing sectors in order to assess early incidence of OA in these "at risk" occupations according to exposure duration, and to identify risk factors of OA.
Methods: This study is a longitudinal retrospective study with a nested case-control to identify risk factors of OA. The assessment of incidence evolution is made by exploring a series of promotions (or retrospective cohorts) with increasing duration since at work. The study population is composed of subjects who graduated between 2001 and 2006 in sectors where they experience exposure to organic or inorganic allergenic or irritant compounds (with an objective of 150 subjects by year) and 250 young workers with no specific occupational exposure.
This study is a descriptive, monocentric, longitudinal and retrospective study with cross-sectional measurements.
Observational Model: Cohort, Time Perspective: Retrospective
Central Hospital, Nancy, France
Published on BioPortfolio: 2014-08-27T03:14:52-0400
The general objective of this multicenter, international study is to perform a multivariate descriptive analysis of a large population of well-defined subjects with sensitizer-induced OA a...
To evaluate airway inflammation in persons with asthma exposed to endotoxin, a common occupational air contaminant. Subjects are subsequently challenged with allergen.
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Cleaning agents are now a common cause of occupational asthma (OA) worldwide. Irritant airway and sensitization mechanisms are implicated for a variety of old and new agents.
Isocyanates are major causes of occupational asthma but susceptibility and mechanisms of Diisocyanate Asthma (DA) remain uncertain.
[This corrects the article DOI: 10.1371/journal.pone.0193144.].
Exposure to isocyanates has consistently been reported as the most common cause of occupational asthma. The objectives of this study were to assess how many Australian workers are currently exposed to...
Asthma attacks caused, triggered, or exacerbated by OCCUPATIONAL EXPOSURE.
Medical specialty concerned with the promotion and maintenance of the physical and mental health of employees in occupational settings.
The branch of dentistry concerned with maintaining oral health of employees in occupational environments.
Noise present in occupational, industrial, and factory situations.
Hospital department responsible for the administration and provision of any occupational or work activity for remedial purposes.
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Asthma is caused by inflammation of small tubes, called bronchi, which carry air in and out of the lungs. If you have asthma, the bronchi will be inflamed and more sensitive than normal. When you come into contact with something that irritates your...