Study of Preoperative Management of Angiotensin Converting Enzyme Inhibitor (ACEi) and Angiotensin Receptor Blocker (ARB) Medications

2014-08-27 03:15:03 | BioPortfolio


Patients on a stable dose of ACE inhibitor or ARB medication who are scheduled for elective surgery will be randomized to take their ACE inhibitor or ARB up to and including the morning of surgery, or to hold them a day prior to the surgery. The patients will be followed for 30 days after surgery to assess any adverse health outcomes.

Study Design

Allocation: Randomized, Control: Active Control, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Investigator, Outcomes Assessor), Primary Purpose: Treatment




Preoperative ACEi/ARB management


London Health Sciences Centre
N6A 5A5




Lawson Health Research Institute

Results (where available)

View Results


Published on BioPortfolio: 2014-08-27T03:15:03-0400

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Medical and Biotech [MESH] Definitions

Care given during the period prior to undergoing surgery when psychological and physical preparations are made according to the special needs of the individual patient. This period spans the time between admission to the hospital to the time the surgery begins. (From Dictionary of Health Services Management, 2d ed)

A cardioselective beta-1-adrenergic blocker. It is effective in the management of hypertension and angina pectoris.

Participation of employees with management as a labor-management team, in decisions pertaining to the operational activities of the organization or industry.

The management of all procurement, distribution, and storage of equipment and supplies, as well as logistics management including laundry, processing of reusables, etc.

A potassium-channel opening vasodilator that has been investigated in the management of hypertension. It has also been tried in patients with asthma. (Martindale, The Extra Pharmacopoeia, 30th ed, p352)

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