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Tobacco Dependence Treatment for Asian Americans

2014-08-27 03:15:04 | BioPortfolio

Summary

Smoking is very common among Asian Americans; yet, research on understanding and treating nicotine addiction in this group is very limited. Korean men have been known for very high smoking rates and the highest cancer death rate related to smoking. In contrast, Korean women tend to initiate smoking as they acculturate into social norms of American women. To help Korean smokers in the United States quit smoking, smoking cessation intervention may neet to be culturally adapted and a family-involved approach. The proposed research plan has two phases and evaluates smoking cessation intervention with Korean Americans (N = 164, 50% women). Phase 1 is a pilot study that is aimed at developing an intervention manual of Motivational Interviewing intervention in combination with nicotine patch. Phase 2 is a clinical trial comparing outcomes of the intervention between intervention group and control group. The control group receives only nicotine patches and management of the side effects. In contrast, the intervention group receives culturally adapted motivational interviewing intervention.

Study Design

Allocation: Randomized, Control: Active Control, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Conditions

Tobacco Dependence

Intervention

transdermal nicotine patch, motivational interviewing with cultural adaptation

Location

University of Massachusetts Medical School
Worcester
Massachusetts
United States
01652

Status

Recruiting

Source

University of Massachusetts, Worcester

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:15:04-0400

Clinical Trials [1245 Associated Clinical Trials listed on BioPortfolio]

Non-Nicotine Agents for Smoking Cessation

The primary objective of this study is to determine which is the better approach to smoking cessation in veterans: bupropion combined with transdermal nicotine or high dose nicotine replac...

The Effects of Nicotine on Cognition in Schizophrenia

Patients with schizophrenia have a variety cognitive deficits and nicotine has been shown to normalize some of these deficits. The purpose of this study is to investigate the effects of ni...

An Effectiveness Trial of Maintenance Therapy for Nicotine Dependence

The transdermal nicotine patch is the most widely used form of tobacco dependence treatment in the US and Europe, but most smokers are unable to successfully quit with this form of treatme...

Memory Improvement Through Nicotine Dosing (MIND) Study

The purpose of the study is to see if daily transdermal nicotine is able to produce a significant cognitive, clinical and functional improvement in participants with MCI. Neuronal nicotini...

Nicotine Patch Trial in Syrian Primary Care Settings

The study is a two-arm, parallel group, randomized, placebo-controlled, double blind trial, conducted at four primary health care centers in Aleppo, Syria, to test the efficacy of transder...

PubMed Articles [3221 Associated PubMed Articles listed on BioPortfolio]

A preclinical evaluation of a programmable CNT membrane device for transdermal nicotine delivery in hairless guinea pigs.

Nicotine replacement therapy in the form of transdermal nicotine patches and nicotine gums combined with behavioral counseling still has a low smoking cessation rate of 25%. A promising approach to sm...

Phase IIb Trial of an α7 Nicotinic Receptor Partial Agonist With and Without Nicotine Patch for Withdrawal-Associated Cognitive Deficits and Tobacco Abstinence.

The objective of this study was to determine whether a novel α7 nicotinic acetylcholine receptor partial agonist improves cognition during nicotine withdrawal and improves abstinence rates. To do so,...

Randomized, double-blind, crossover study of the adhesiveness of two formulations of rotigotine transdermal patch in patients with Parkinson's disease.

In patch-based transdermal drug delivery, adhesiveness is critical for safe and effective treatment, especially in Parkinson's disease (PD) where excessive sweating is common. This study compared the ...

Motivational Interviewing in Preventing Early Childhood Caries in Primary Healthcare: A Community-based Randomized Cluster Trial.

To assess the effectiveness of motivational interviewing in preventing early childhood caries compared with conventional oral health education.

Enhancing Self-Care Management of Interdialytic Fluid Weight Gain in Patients on Hemodialysis: A Pilot Study Using Motivational Interviewing.

Patients receiving hemodialysis are challenged with restricting their fluid intake to ensure appropriate interdialytic weight gains. While nurses endeavor to promote selfcare, the ability to manage fl...

Medical and Biotech [MESH] Definitions

A medicated adhesive patch placed on the skin to deliver a specific dose of medication into the bloodstream.

It is a client-centered, directive method for eliciting intrinsic motivation to change using open-ended questions, reflective listening, and decisional balancing. This nonjudgmental, nonconfrontational interviewing style is designed to minimize a patient's resistance to change by creating an interaction that supports open discussion of risky or problem behavior.

Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.

An electrophysiologic technique for studying cells, cell membranes, and occasionally isolated organelles. All patch-clamp methods rely on a very high-resistance seal between a micropipette and a membrane; the seal is usually attained by gentle suction. The four most common variants include on-cell patch, inside-out patch, outside-out patch, and whole-cell clamp. Patch-clamp methods are commonly used to voltage clamp, that is control the voltage across the membrane and measure current flow, but current-clamp methods, in which the current is controlled and the voltage is measured, are also used.

Cultural and linguistic competence is a set of congruent behaviors, attitudes, and policies that come together in a system, agency, or among professionals that enables effective work in cross-cultural situations. Competence implies the capacity to function effectively as an individual and an organization within the context of the cultural beliefs, behaviors, and needs presented by consumers and their communities.

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