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Smoking is very common among Asian Americans; yet, research on understanding and treating nicotine addiction in this group is very limited. Korean men have been known for very high smoking rates and the highest cancer death rate related to smoking. In contrast, Korean women tend to initiate smoking as they acculturate into social norms of American women. To help Korean smokers in the United States quit smoking, smoking cessation intervention may neet to be culturally adapted and a family-involved approach. The proposed research plan has two phases and evaluates smoking cessation intervention with Korean Americans (N = 164, 50% women). Phase 1 is a pilot study that is aimed at developing an intervention manual of Motivational Interviewing intervention in combination with nicotine patch. Phase 2 is a clinical trial comparing outcomes of the intervention between intervention group and control group. The control group receives only nicotine patches and management of the side effects. In contrast, the intervention group receives culturally adapted motivational interviewing intervention.
Allocation: Randomized, Control: Active Control, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
transdermal nicotine patch, motivational interviewing with cultural adaptation
University of Massachusetts Medical School
University of Massachusetts, Worcester
Published on BioPortfolio: 2014-08-27T03:15:04-0400
The primary objective of this study is to determine which is the better approach to smoking cessation in veterans: bupropion combined with transdermal nicotine or high dose nicotine replac...
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To assess whether adapted motivational interviewing (MI) has any impact on the proportion of participants who subsequently underwent surgery or laser treatment for glaucoma.
A medicated adhesive patch placed on the skin to deliver a specific dose of medication into the bloodstream.
It is a client-centered, directive method for eliciting intrinsic motivation to change using open-ended questions, reflective listening, and decisional balancing. This nonjudgmental, nonconfrontational interviewing style is designed to minimize a patient's resistance to change by creating an interaction that supports open discussion of risky or problem behavior.
Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
An electrophysiologic technique for studying cells, cell membranes, and occasionally isolated organelles. All patch-clamp methods rely on a very high-resistance seal between a micropipette and a membrane; the seal is usually attained by gentle suction. The four most common variants include on-cell patch, inside-out patch, outside-out patch, and whole-cell clamp. Patch-clamp methods are commonly used to voltage clamp, that is control the voltage across the membrane and measure current flow, but current-clamp methods, in which the current is controlled and the voltage is measured, are also used.
Cultural and linguistic competence is a set of congruent behaviors, attitudes, and policies that come together in a system, agency, or among professionals that enables effective work in cross-cultural situations. Competence implies the capacity to function effectively as an individual and an organization within the context of the cultural beliefs, behaviors, and needs presented by consumers and their communities.
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