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Patients with liver cirrhosis are at risk for development of renal failure, usually after a precipitating event such as infection or bleeding. This form of renal failure has a high morbidity and mortality and may be partly caused by increased intra-abdominal pressure secondary to ascites. Recent studies have shown that paracentesis (and the resulting decreased IAP) can increase urinary output and decrease renal arterial resistive index in patients with hepatorenal syndrome (a very pronounced form of renal failure in cirrhosis patients). The aim of this study is to evaluate the influence of Paracentesis on intra-abdominal pressure and kidney function in critically ill patients with liver cirrhosis and ascites across a wider range of kidney function. Kidney function will be evaluated using several estimates of glomerular filtration rate and measures of kidney injury i.e. cystatin C, serum NGAL, creatinine clearance, urinary output and renal arterial resistive index.
Observational Model: Cohort, Time Perspective: Prospective
University Hospital Ghent
University Hospital, Ghent
Published on BioPortfolio: 2014-07-24T14:06:47-0400
The aim of our study was to evaluate hemodynamic changes during routine paracentesis in tense ascites using non-invasive inert gas rebreathing.
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A procedure in which fluid is withdrawn from a body cavity via a trocar and cannula, needle, or other hollow instrument.
Health care provided to a critically ill patient during a medical emergency or crisis.
Registered nurses with graduate degrees in nursing who provide care to pediatric patients who are acutely or critically ill.
A nursing specialty that deals specifically with the care of patients who are critically ill.
An acronym for Acute Physiology and Chronic Health Evaluation, a scoring system using routinely collected data and providing an accurate, objective description for a broad range of intensive care unit admissions, measuring severity of illness in critically ill patients.
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