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Montelukast and Inhaled Nasal Steroid Tx in Adult Obstructive Sleep Apnea (OSA)

2014-08-27 03:15:05 | BioPortfolio

Summary

In children with mild apnea combined therapy with an inhaled nasal steroid and a medication that decreased nasal congestion (montelukast) was shown to be effective. We are testing to see if this combination works in adults with mild apnea as well.

Description

40 adults with mild OSA (< 5 apneas/hypopneas per hour of sleep) will receive either a combination of two medicines that decrease nasal congestion-montelukast and nasal budesonide-or a placebo pill and nasal spray. After 3 months of therapy, a repeat sleep study will be done to determine the differences, if any, in the frequency of sleep disordered breathing in the two groups.

Study Design

Allocation: Randomized, Control: Placebo Control, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment

Conditions

Obstructive Sleep Apnea

Intervention

budesonide nasal spray and a montelukast pill, Placebo: sugar pill and salt water nasal spray

Location

Romaker & Associates
Kansas City
Missouri
United States
64111

Status

Not yet recruiting

Source

Romaker & Associates

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:15:05-0400

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