Vitrification Versus Spontaneous Conception
Summary
Great scientific effort has been made to improve practical as well as economical procedures of modern assisted reproduction.
In the last years a shift from the well established method of slow-rate freezing to vitrification of 2PN zygotes and embryos could be observed. Like any other method of cryopreservation, the outcome of vitrification will be affected by several factors related to technique itself, its practical management and patient characteristics.
The investigators want to investigate the influence of vitrification on the outcome of of 2PN oocytes, pregnancy and infant health.
A Comparison between a cohort of spontaneous conceived children and children of vitrified 2PN oocytes is planned.
Study Design
Observational Model: Case Control, Time Perspective: Retrospective
Conditions
Pregnancy
Intervention
Observation
Location
Schleswig- Holstein University, Campus Lübeck, Department of Reproductive Medicine
Lübeck
Schleswig- Holstein
Germany
D-23538
Status
Recruiting
Source
University of Luebeck
Results (where available)
Links
- Source: http://clinicaltrials.gov/show/NCT01088425
- Information obtained from ClinicalTrials.gov on July 15, 2010
Published on BioPortfolio: 2014-08-27T03:15:10-0400
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Medical and Biotech [MESH] Definitions
Pregnancy Proteins
Proteins produced by organs of the mother or the PLACENTA during PREGNANCY. These proteins may be pregnancy-specific (present only during pregnancy) or pregnancy-associated (present during pregnancy or under other conditions such as hormone therapy or certain malignancies.)
Observation
The act of regarding attentively and studying facts and occurrences, gathering data through analyzing, measuring, and drawing conclusions, with the purpose of applying the observed information to theoretical assumptions. Observation as a scientific method in the acquisition of knowledge began in classical antiquity; in modern science and medicine its greatest application is facilitated by modern technology. Observation is one of the components of the research process.
Pregnancy In Diabetics
The state of PREGNANCY in women with DIABETES MELLITUS. This does not include either symptomatic diabetes or GLUCOSE INTOLERANCE induced by pregnancy (DIABETES, GESTATIONAL) which resolves at the end of pregnancy.
Pregnancy, Unplanned
Unintended accidental pregnancy, including pregnancy resulting from failed contraceptive measures.
Pregnancy, High-risk
Pregnancy in which the mother and/or FETUS are at greater than normal risk of MORBIDITY or MORTALITY. Causes include inadequate PRENATAL CARE, previous obstetrical history (ABORTION, SPONTANEOUS), pre-existing maternal disease, pregnancy-induced disease (GESTATIONAL HYPERTENSION), and MULTIPLE PREGNANCY, as well as advanced maternal age above 35.
