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Pilot Study for Cell Based Therapies in Patients With Asthma

2014-08-27 03:15:11 | BioPortfolio

Summary

The aim of this study is to investigate the immunomodulatory potential of Isolated Plasmacytoide Dendritic Cells (pDCs) and Regulatory T-cells (TREGs) isolated with clinical grade magnetic bead isolations techniques (MACS®) on the antigen presenting cell-induced proliferation of lymphocytes after allergen uptake in an in vitro cell culture system.

Description

pDCs as well as TREGs will be co-incubated with generated allergen presenting cells, lymphocytes, and allergen. For in vitro experimentation immune cells will be collected from blood of grass mix or house dust mite sensitized atopic/asthmatic patients.

Study Design

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Basic Science

Conditions

Asthma

Intervention

Blood donation

Status

Enrolling by invitation

Source

Fraunhofer-Institute of Toxicology and Experimental Medicine

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:15:11-0400

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