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Corneal Endothelium Morphology and Central Thickness in Type II Diabetes Mellitus and Normal Subjects

2014-08-27 03:15:18 | BioPortfolio

Summary

The purpose of this study is to compare corneal endothelium morphology and central thickness in type II Diabetes Mellitus and normal subjects with special reference to glycemic status.

Description

Diabetes might influence the health of the corneal endothelium. Older studies have presented different results and the glycemic status of the patients have not been reported. In this study we examine the corneal endothelium morphology and central thickness in type II Diabetes Mellitus and normal subjects with modern specular microscopy. Each patient and control is examined once ("entry to study").

Study Design

Observational Model: Case Control, Time Perspective: Cross-Sectional

Conditions

Corneal Dystrophy

Location

Frederiksberg University Eye Clinque
Frederiksberg
Denmark
2000

Status

Recruiting

Source

Frederiksberg University Hospital

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:15:18-0400

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Medical and Biotech [MESH] Definitions

An autosomal dominant form of hereditary corneal dystrophy due to a defect in cornea-specific KERATIN formation. Mutations in the genes that encode KERATIN-3 and KERATIN-12 have been linked to this disorder.

Loss of CORNEAL ENDOTHELIUM usually following intraocular surgery (e.g., cataract surgery) or due to FUCHS' ENDOTHELIAL DYSTROPHY; ANGLE-CLOSURE GLAUCOMA; IRITIS; or aging.

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A type I keratin that is found associated with the KERATIN-3 in the CORNEA and is regarded as a marker for corneal-type epithelial differentiation. Mutations in the gene for keratin-12 have been associated with MEESMANN CORNEAL EPITHELIAL DYSTROPHY.

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