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Study to Evaluate the Efficacy, Safety and Tolerability of N1539

2014-08-27 03:15:18 | BioPortfolio

Summary

To determine the analgesic efficacy, duration of effect, and safety of single doses of N1539 in subjects undergoing open abdominal hysterectomy

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment

Conditions

Hysterectomy

Intervention

N1539, N1539, N1539, N1539, placebo, Morphine, N1539

Location

Tbilisi
Georgia
0186

Status

Recruiting

Source

Elan Drug Delivery Inc

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:15:18-0400

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PubMed Articles [1152 Associated PubMed Articles listed on BioPortfolio]

Effects of pregabalin on postoperative pain after hysterectomy under spinal anesthesia with intrathecal morphine: a randomized controlled trial.

To determine if preoperative pregabalin could decrease 24-h postoperative morphine consumption after spinal anesthesia with intrathecal morphine compared with placebo.

Robotic radical hysterectomy is superior to laparoscopic radical hysterectomy and open radical hysterectomy in the treatment of cervical cancer.

Cervical cancer (CC) continues to be a global burden for women, with higher incidence and mortality rates reported annually. Many countries have witnessed a dramatic reduction in the prevalence of CC ...

Cost evaluation, quality of life and pelvic organ function of three approaches to hysterectomy for benign uterine conditions: study protocol for a randomized controlled trial.

Hysterectomy is the commonest major gynaecological surgery. Although there are many approaches to hysterectomy, which depend on clinical criteria, certain patients may be eligible to be operated in an...

Hysterectomy is associated with higher risk of coronary artery disease: A nationwide retrospective cohort study in Taiwan.

Hysterectomy is a common procedure for benign pathologies of the uterus. Reduced production of estrogen following hysterectomy has been reported. Yet the association between hysterectomy and coronary ...

Nationwide Trends in the Utilization of and Payments for Hysterectomy in the United States Among Commercially Insured Women.

Laparotomy followed by inpatient hospitalization has traditionally been the most common surgical care for hysterectomy. The financial implications of the increased use of laparoscopy and outpatient hy...

Medical and Biotech [MESH] Definitions

The principal alkaloid in opium and the prototype opiate analgesic and narcotic. Morphine has widespread effects in the central nervous system and on smooth muscle.

An opioid analgesic made from MORPHINE and used mainly as an analgesic. It has a shorter duration of action than morphine.

Strong dependence, both physiological and emotional, upon morphine.

Analogs or derivatives of morphine.

Excision of the uterus.

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