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Assessment of Blood and Follicular Fluid Immune Cell Constitution in Patients Undergoing in Vitro Fertilization

2014-08-27 03:15:22 | BioPortfolio

Summary

The etiology of infertility in the majority of patients with poor response to ovarian stimulation remains unknown. This study will investigate the role of immune cells (T cells, B cells, dendritic cells and NK cells), that constitute the immune system which normally fights infection and cancer. We, the investigators, have found that specialized NK cells that help with new blood vessel formation, are found in the fluid surrounding the egg during IVF, only in patients with good response to ovarian stimulation. We now wish to expand our studies and correlate our findings to ovarian blood flow , as measured by 3D ultrasound and to the presence of other cells in the immune system.

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Conditions

Infertility, Female

Location

Hillel Yaffe Medical Center
Hadera
Israel
38100

Status

Not yet recruiting

Source

Hillel Yaffe Medical Center

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:15:22-0400

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Medical and Biotech [MESH] Definitions

Diminished or absent ability of a female to achieve conception.

Inability to reproduce after a specified period of unprotected intercourse. Reproductive sterility is permanent infertility.

The inability of the male to effect FERTILIZATION of an OVUM after a specified period of unprotected intercourse. Male sterility is permanent infertility.

MYCOBACTERIUM infections of the female reproductive tract (GENITALIA, FEMALE).

Tumor or cancer of the female reproductive tract (GENITALIA, FEMALE).

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