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Salivary Proteome and Sensitivity to Bitterness

2014-08-27 03:15:30 | BioPortfolio

Summary

This study aims to establish whether the protein composition of healthy males contribute to their sensitivity to the bitterness of caffeine.

Study Design

Primary Purpose: Basic Science

Conditions

Healthy

Intervention

caffeine

Status

Completed

Source

Institut National de la Recherche Agronomique

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:15:30-0400

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Medical and Biotech [MESH] Definitions

A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Caffeine's most notable pharmacological effect is as a central nervous system stimulant, increasing alertness and producing agitation. It also relaxes SMOOTH MUSCLE, stimulates CARDIAC MUSCLE, stimulates DIURESIS, and appears to be useful in the treatment of some types of headache. Several cellular actions of caffeine have been observed, but it is not entirely clear how each contributes to its pharmacological profile. Among the most important are inhibition of cyclic nucleotide PHOSPHODIESTERASES, antagonism of ADENOSINE RECEPTORS, and modulation of intracellular calcium handling.

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A plant genus of the family STERCULIACEAE. This is the source of the kola nut which contains CAFFEINE and is used in popular beverages.

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