A Study to Evaluate Long-term Impact of VARIVAX Among Children and Adolescents

2014-08-27 03:15:35 | BioPortfolio


The purpose of these continuing post-licensure studies is to evaluate the long-term effectiveness of VARIVAX® [Varicella Virus Vaccine Live (Oka/Merck)] and to assess the impact of the vaccine on the epidemiology of varicella and herpes zoster

Study Design

Observational Model: Cohort, Time Perspective: Prospective




Active, not recruiting



Results (where available)

View Results


Published on BioPortfolio: 2014-08-27T03:15:35-0400

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Safety of a Second Dose of Biken's Varicella Vaccine

The objective of the present study is to assess and document the safety of a second dose of Varicella Biken vaccine administered at 4 to 6 years of age in healthy children having previousl...

A Safety and Immune Study of 2 Types of GlaxoSmithKline's Varicella Vaccines Given as a 2-doses Course to Healthy Children 12-23 Months of Age.

The purpose of this study is to evaluate the safety and immunogenicity of 2 formulations of GSK Biologicals' varicella vaccines given as a 2-dose course in the second year of life.

Varicella Vaccination With Pulmicort

A study to determine whether treatment with Pulmicort in children has any effect on the varicella vaccine

A Blind, Randomized and Controlled Study of Live Attenuated Varicella Vaccines

The purpose of this study is to evaluate the protective effect, safety and immunogenicity of a live attenuated varicella vaccine in healthy children.

Study of Two Formulations of GSK Biologicals' Varicella Vaccine

The aim of this study is to evaluate a modified formulation of GSK Biologicals' live attenuated varicella vaccine. In vivo pre-clinical data show this change has no negative impact on vacc...

PubMed Articles [73 Associated PubMed Articles listed on BioPortfolio]

Economic burden of varicella complications in two referral centers in Mexico.

Varicella-zoster virus causes varicella (chicken-pox), mainly in young children. Most cases are mild but serious complications can occur, resulting in significant morbidity and mortality. The objectiv...

Outbreak of varicella in preschool children despite one-dose vaccination.

Kurugöl Z, Gökçe Ş. Outbreak of varicella in preschool children despite one-dose vaccination. Turk J Pediatr 2018; 60: 56-62. In Turkey, a single-dose varicella vaccine was introduced into the Nat...

Plaque psoriasis following Kawasaki disease and varicella.

We describe the case of a 15-month-old boy with Kawasaki disease who developed varicella 7 days after the beginning of the disease and diffuse plaque psoriasis after 43 days. Associations between Ka...

Severe and complicated varicella and associated genotypes 10 years after introduction of a one dose varicella vaccine program.

This national, sentinel prospective study aimed to identify children with severe hospitalized varicella despite availability of universal one-dose vaccination from 2005 and determine associations betw...

Implementing Universal Varicella Vaccination in Europe: The Path Forward.

Varicella is a common vaccine-preventable disease that usually presents as a mild disorder but can lead to severe complications. Before the implementation of universal varicella vaccination (UVV) in s...

Medical and Biotech [MESH] Definitions

Inflammation of brain tissue caused by infection with the varicella-zoster virus (HERPESVIRUS 3, HUMAN). This condition is associated with immunocompromised states, including the ACQUIRED IMMUNODEFICIENCY SYNDROME. Pathologically, the virus tends to induce a vasculopathy and infect oligodendrocytes and ependymal cells, leading to CEREBRAL INFARCTION, multifocal regions of demyelination, and periventricular necrosis. Manifestations of varicella encephalitis usually occur 5-7 days after onset of HERPES ZOSTER and include HEADACHE; VOMITING; lethargy; focal neurologic deficits; FEVER; and COMA. (From Joynt, Clinical Neurology, 1996, Ch 26, pp29-32; Hum Pathol 1996 Sep;27(9):927-38)

The type species of VARICELLOVIRUS causing CHICKENPOX (varicella) and HERPES ZOSTER (shingles) in humans.

A live, attenuated varicella virus vaccine used for immunization against chickenpox. It is recommended for children between the ages of 12 months and 13 years.

A nucleoside antibiotic isolated from Streptomyces antibioticus. It has some antineoplastic properties and has broad spectrum activity against DNA viruses in cell cultures and significant antiviral activity against infections caused by a variety of viruses such as the herpes viruses, the VACCINIA VIRUS and varicella zoster virus.


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