Clinical Outcomes in Candidemia Patients Based on in Vitro Susceptibility

2014-08-27 03:15:35 | BioPortfolio


Susceptibility testing is commonly employed in patients with bacterial infections in order to guide rational use of antibiotics; however, the use of antifungal susceptibility testing is limited due to lack of availability, costs, and delays in receiving results. The goals of antifungal susceptibility testing should mirror those of antibacterial susceptibility testing: to predict clinical response or failure. Additionally, susceptibility reports should be used as a guide for physicians when transitioning patients from parenteral to oral antifungal agents. Currently, it is unknown whether antifungal susceptibility testing impacts treatment decisions in hospitals that routinely perform Candida susceptibility testing. The purpose of this study is to evaluate the changes in antifungal treatment based on in vitro susceptibility reports and how these decisions affect mortality, recurrence of infection, and length of hospital stay in candidemia patients.

Study Design

Observational Model: Cohort, Time Perspective: Retrospective


Blood Stream Infections


Active, not recruiting


University of Houston

Results (where available)

View Results


Published on BioPortfolio: 2014-08-27T03:15:35-0400

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Medical and Biotech [MESH] Definitions

The introduction of whole blood or blood component directly into the blood stream. (Dorland, 27th ed)

Obstruction of a blood vessel (embolism) by a blood clot (THROMBUS) in the blood stream.

Blocking of a blood vessel by an embolus which can be a blood clot or other undissolved material in the blood stream.

A collective term for pathological conditions which are caused by the formation of a blood clot (THROMBUS) in a blood vessel, or by blocking of a blood vessel with an EMBOLUS, undissolved materials in the blood stream.

Obstruction of a vein or VEINS (embolism) by a blood clot (THROMBUS) in the blood stream.

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