Topics

Potassium-Magnesium Citrate as a Blood Pressure Lowering Agent in Hypertensive Patients

2014-08-27 03:15:41 | BioPortfolio

Summary

The goal of this study is to compare the effects of Potassium Magnesium Citrate to Potassium Chloride on blood pressure among patients with pre-hypertension or mild hypertension. We will also test whether Potassium Magnesium Citrate increases excretion of large amounts of sodium in the urine.

Study Design

Allocation: Randomized, Control: Active Control, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Supportive Care

Conditions

Pre-Hypertension

Intervention

Potassium, Magnesium, Citrate, Potassium Chloride

Location

Dallas VA Medical Center
Dallas
Texas
United States
75216

Status

Recruiting

Source

University of Texas Southwestern Medical Center

Results (where available)

View Results

Links

Published on BioPortfolio: 2014-08-27T03:15:41-0400

Clinical Trials [2302 Associated Clinical Trials listed on BioPortfolio]

Value of Liquid Potassium Magnesium Citrate in Controlling Hypertension

In the DASH (Dietary Approaches to Stop Hypertension) trials, a diet rich in fruits, vegetables, nuts and dairy products, and limited in fat content, was shown to be useful in controlling ...

Potassium Supplementation in CKD

The current high-sodium, low-potassium diet contributes to the high prevalence of high blood pressure (hypertension). Indeed, the anti-hypertensive effects of potassium supplementation are...

Preventing Metabolic Side Effects of Thiazide Diuretics With KMgCitrate

Chlorthalidone (CTD) may produce various metabolic disturbances, including hypokalemia, activation of Renin-Angiotensin- Aldosterone (RAA) system, oxidative stress, dyslipidemia, Fibroblas...

Safety of Continuous Potassium Chloride Infusion in Critical Care

Patients in critical care often require supplemental potassium chloride if levels in their blood are below acceptable level. Common practice is to administer a single dose of potassium chl...

Effects of Potassium Salts on Blood Pressure and Target Organ Damage

The purpose of this study is to determine the effect of potassium chloride and potassium bicarbonate on blood pressure and also to determine whether increasing potassium intake has benefic...

PubMed Articles [3708 Associated PubMed Articles listed on BioPortfolio]

ESR investigation on the potential use of potassium citrate as a dosimeter material.

Un-irradiated potassium citrate exhibited a weak ESR singlet at g = 2.0045 ± 0.0003 with peak-to-peak line-width of ΔH = 0.16 mT. However, multi-resonance signals spreading over a magn...

Daily intake of sodium and potassium among diverse US Hispanics/Latinos, the Hispanic Community Health Study/Study of Latinos.

High sodium and low potassium consumption are risk factors for hypertension. The ojectives of this study were to describe usual daily intake of sodium and potassium among US Hispanics/Latinos of diver...

Molecular Dynamics and Neutron Scattering Studies of Potassium Chloride in Aqueous Solution.

Neutron Diffraction with Isotopic Substitution (NDIS) experiments were done on both natural abundance potassium and isotopically-labeled 41KCl heavy water solutions to characterize the solvent structu...

MXene-Based Dendrite-Free Potassium Metal Batteries.

Potassium metal batteries are considered as attractive alternatives beyond lithium-ion batteries. However, uncontrollable dendrite growth on the potassium metal anode has restrained their practical ap...

Effect of Dietary Potassium Restriction on Serum Potassium, Disease Progression, and Mortality in Chronic Kidney Disease: A Systematic Review and Meta-Analysis.

Low-potassium diets are recommended to reduce serum potassium (Sk) and prevent complications of chronic kidney disease (CKD), but evidence underpinning this recommendation has not been systematically ...

Medical and Biotech [MESH] Definitions

A subclass of symporters that specifically transport SODIUM CHLORIDE and POTASSIUM CHLORIDE across cellular membranes in a tightly coupled process.

Agents that inhibit SODIUM-POTASSIUM-CHLORIDE SYMPORTERS which are concentrated in the thick ascending limb at the junction of the LOOP OF HENLE and KIDNEY TUBULES, DISTAL. They act as DIURETICS. Excess use is associated with HYPOKALEMIA and HYPERGLYCEMIA.

A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.

Magnesium chloride. An inorganic compound consisting of one magnesium and two chloride ions. The compound is used in medicine as a source of magnesium ions, which are essential for many cellular activities. It has also been used as a cathartic and in alloys.

Stable potassium atoms that have the same atomic number as the element potassium, but differ in atomic weight. K-41 is a stable potassium isotope.

More From BioPortfolio on "Potassium-Magnesium Citrate as a Blood Pressure Lowering Agent in Hypertensive Patients"

Quick Search

Relevant Topics

Nephrology - kidney function
Nephrology is a specialty of medicine and pediatrics that concerns itself with the study of normal kidney function, kidney problems, the treatment of kidney problems and renal replacement therapy (dialysis and kidney transplantation). Systemic conditions...

Cardiology
Cardiology is a specialty of internal medicine.  Cardiac electrophysiology : Study of the electrical properties and conduction diseases of the heart. Echocardiography : The use of ultrasound to study the mechanical function/physics of the h...

Nutrition
Within medicine, nutrition (the study of food and the effect of its components on the body) has many different roles. Appropriate nutrition can help prevent certain diseases, or treat others. In critically ill patients, artificial feeding by tubes need t...


Searches Linking to this Trial